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  1. Behcet’s disease (BD) is a multisystem and multifactorial autoimmune disease characterized by relapsing episodes of oral aphthae, genital ulcers, and ocular and skin lesions. Toll-like receptor 9 (TLR9) has pro-i...

    Authors: Zahra Tadayon, Seyed Abolhassan Shahzadeh Fazeli, Nasser Gholijani and Gholamreza Daryabor
    Citation: BMC Rheumatology 2024 8:13
  2. Exercise and physical activity (EPA) are recommended for people with chronic musculoskeletal disease; however, lower levels of engagement with EPA has been consistently reported in people from the South Asian ...

    Authors: Nasimah Maricar, Gillian Yeowell, Trixy David, Behram Khan, Anne Barton, Kimme L Hyrich and Sandra E Hartley
    Citation: BMC Rheumatology 2024 8:12
  3. To describe the evidence of methotrexate (MTX) initiation strategies in patients with rheumatoid arthritis (RA) and, in the case of non-responders, analyse the efficacy and safety of route and dose optimisation.

    Authors: Esteban Rubio-Romero, César Díaz-Torné, María José Moreno-Martínez and Julen De-Luz
    Citation: BMC Rheumatology 2024 8:11
  4. Despite continuous improvements in anti-rheumatic pharmacological treatment, people with chronic inflammatory arthritis still report substantial disease impact. Based on the framework for complex interventions...

    Authors: Nadine Schäffer Blum, Bente Appel Esbensen, Mikkel Østergaard, Ann Bremander, Oliver Hendricks, Luise Holberg Lindgren, Lena Andersen, Kim Vilbaek Jensen and Jette Primdahl
    Citation: BMC Rheumatology 2024 8:10
  5. Impella is an advanced ventricular assist device frequently used as a bridge to heart transplantation. The association of Impella with increased rates of gout flares has not been studied. Our primary aim is to...

    Authors: Jorge Sinclair De Frías, Shahin Isha, Lorenzo Olivero, Lekhya Raavi, Sai Abhishek Narra, Smit Paghdar, Sadhana Jonna, Parthkumar Satashia, Rachel Hannon, Jessica Blasavage, Layton White, Titilope Olanipekun, Pankaj Bansal, Sean Kiley, Juan Carlos Leoni, Jose Nativí…
    Citation: BMC Rheumatology 2024 8:9
  6. In accordance with the EULAR recommendations, the Danish Hospital for Rheumatic Diseases have systematically invited patients with rheumatoid arthritis (RA) to cardiovascular (CV) risk assessment since 2011. P...

    Authors: Julie Katrine Karstensen, Ann Bremander, Jeanette Reffstrup Christensen and Jette Primdahl
    Citation: BMC Rheumatology 2024 8:8
  7. There is an increased risk of cardiovascular disease in people with many rheumatic diseases. The primary objective of this study was to evaluate cardiovascular disease hospitalizations in Alaska for people wit...

    Authors: Elizabeth D. Ferucci and Peter Holck
    Citation: BMC Rheumatology 2024 8:7
  8. To explore the trajectory of, and factors contributing to, achievement of individual criteria of minimal disease activity (MDA) in patients with active psoriatic arthritis (PsA) treated with guselkumab.

    Authors: Laura C. Coates, Proton Rahman, Philip J. Mease, May Shawi, Emmanouil Rampakakis, Alexa P. Kollmeier, Xie L. Xu, Soumya D. Chakravarty, Iain B. McInnes and Lai-Shan Tam
    Citation: BMC Rheumatology 2024 8:6
  9. Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thromb...

    Authors: Zahra A Fazal, Ana Michelle Avina-Galindo, Shelby Marozoff, Jessie Kwan, Na Lu and J. Antonio Avina-Zubieta
    Citation: BMC Rheumatology 2024 8:5
  10. Interstitial lung disease (ILD) related to rheumatoid arthritis (RA) is among the leading causes of death and an essential prognostic factor. There is only limited evidence for the safety of anti-rheumatic dru...

    Authors: Atsuko Tsujii, Kentaro Isoda, Maiko Yoshimura, Akihiko Nakabayashi, Dong-Seop Kim, Tatsuya Tamada, Kurumi Yamamoto and Shiro Ohshima
    Citation: BMC Rheumatology 2024 8:4
  11. Ankylosing spondylitis(AS) is a chronic inflammatory rheumatic disease primarily affecting the spine and sacroiliac joints. While biologic disease-modifying antirheumatic drugs(bDMARDs) and targeted synthetic ...

    Authors: Jie Chang and Gang Wang
    Citation: BMC Rheumatology 2024 8:3
  12. Janus kinase inhibitors (JAKi) are new targeted synthetic disease-modifying antirheumatic drugs (DMARDs) licenced in the UK to treat rheumatoid and psoriatic arthritides. Unlike currently often prescribed biol...

    Authors: Savia de Souza, Ruth Williams and Elena Nikiphorou
    Citation: BMC Rheumatology 2024 8:1
  13. Dry eyes and mouth are symptoms of Sjogren syndrome, which can occur on its own and be referred to as primary Sjogren syndrome or in conjunction with other rheumatic diseases like rheumatoid arthritis and be r...

    Authors: Hagar Elsayed Fakher, Nagat Mohammed El Gazzar, Maaly Mohamed Mabrouk and Doaa Waseem Nada
    Citation: BMC Rheumatology 2023 7:45
  14. Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disease characterized by clinical and pathological diversity. Mitochondrial dysfunction has been identified as a critical pathogenetic factor in ...

    Authors: Haoguang Li, Lu Zhou, Wei Zhou, Xiuling Zhang, Jingjing Shang, Xueqin Feng, Le Yu, Jie Fan, Jie Ren, Rongwei Zhang and Xinwang Duan
    Citation: BMC Rheumatology 2023 7:44
  15. To investigate whether baseline serum cartilage oligomeric matrix protein (COMP), patient characteristics, traditional cardiovascular disease (CVD) risk factors and disease activity over time predict CVD, in e...

    Authors: Emil Rydell, Lennart TH Jacobsson, Tore Saxne and Carl Turesson
    Citation: BMC Rheumatology 2023 7:43
  16. Behcet disease (BD) as a variable vessel vasculitis is mainly characterized by ocular involvement, genital and oral aphthosis, and erythema nodosum. However, major organ involvements including gastrointestinal...

    Authors: Mohammad Nejadhosseinian, Mazyar Babagoli, Seyedeh Tahererh Faezi, Hoda Haerian, Farhad Shahram, Majid Alikhani and Fereydoun Davatchi
    Citation: BMC Rheumatology 2023 7:42
  17. SLE is an autoimmune disease marked by broad immunological dysregulation and multi-system inflammation. Baricitinib is one of the novel treatments for SLE. We conducted this meta-analysis to evaluate its safet...

    Authors: Abdallah R. Allam, Mohamed Salah Alhateem and Abdelrahman Mohamed Mahmoud
    Citation: BMC Rheumatology 2023 7:40
  18. The inflammasome plays an important role in rheumatoid arthritis (RA), which has rarely been systematically reported. The aim of this study was to understand whether the levels of inflammasomes were related to...

    Authors: Qi Jiang, Xin Wang, Xiuping Xu, Liangfeng Hu, Guozhong Zhou, Rui Liu, Guocan Yang and Dawei Cui
    Citation: BMC Rheumatology 2023 7:39
  19. Supporting adherence to medication is an essential part of the treatment and care of patients with rheumatic and musculoskeletal diseases. The Compliance Questionnaire Rheumatology (CQR) measures adherence in ...

    Authors: Line Raunsbæk Knudsen and Annette de Thurah
    Citation: BMC Rheumatology 2023 7:38
  20. While the integration of patient and public involvement (PPI) in clinical research is now widespread and recommended as standard practice, meaningful PPI in pre-clinical, discovery science research is more dif...

    Authors: Gwenda Simons, Rebecca Birch, Joanne Stocks, Elspeth Insch, Rob Rijckborst, Georgiana Neag, Heidi McColm, Leigh Romaniuk, Claire Wright, Bethan E. Phillips, Simon W. Jones, Arthur G. Pratt, Stefan Siebert, Karim Raza and Marie Falahee
    Citation: BMC Rheumatology 2023 7:36
  21. There is increasing research interest in the development of preventive treatment for individuals at risk of rheumatoid arthritis (RA). Previous studies have explored the perceptions of at-risk groups and patie...

    Authors: Imogen Wells, Gwenda Simons, Jasin Philip Kanacherril, Christian D. Mallen, Karim Raza and Marie Falahee
    Citation: BMC Rheumatology 2023 7:35
  22. Clinically significant pericardial effusions and cardiac tamponade in systemic sclerosis (SSc) patients is uncommon and the factors that contribute to progression of pericardial involvement in SSc patients hav...

    Authors: Bikash Basyal, Waqas Ullah and Chris T. Derk
    Citation: BMC Rheumatology 2023 7:34
  23. Traditionally rheumatoid arthritis (RA) trials classify patients as responders and non-responders; they ignore the potential range of treatment responses. Group Based Trajectory Models (GBTMs) provide a more r...

    Authors: Fowzia Ibrahim, Ian C Scott, David L Scott and Salma Ahmed Ayis
    Citation: BMC Rheumatology 2023 7:33
  24. Rheumatic and musculoskeletal diseases (RMDs) require a tailored follow-up that can be enhanced by the implementation of innovative tools. The Digireuma study aimed to test the feasibility of a hybrid follow-u...

    Authors: D. Benavent, L. Fernández-Luque, M. Sanz-Jardón, I. Bilionis, M. Novella-Navarro, V. Navarro-Compán, P. L. González-Sanz, E. Calvo, L. Lojo, A. Balsa and Ch Plasencia-Rodríguez
    Citation: BMC Rheumatology 2023 7:32
  25. Although reduced work ability is a substantial problem among people with inflammatory arthritis (IA), work ability is an underexposed area in clinical practice. Evidence on vocational interventions in IA is li...

    Authors: N. F. Bakker, S. F. E. van Weely, N. Hutting, Y. F. Heerkens, J. A. Engels, J. B. Staal, M. van der Leeden, A. Boonen, W. B. van den Hout, T. P. M. Vliet Vlieland and J. Knoop
    Citation: BMC Rheumatology 2023 7:31
  26. Cardiac tumours are rare, and clinical manifestations depend on the anatomical location. Symptoms can be the result of cardiac outflow anomalies, constitutional features such as fever, loss of weight, and/or p...

    Authors: Natasha Ung, Carmella Gunasingam, Ken Cai, Nicholas Manolios, Angela Bayly, Phuong Dinh, Yishay Orr, Preeti Choudhary and Peter Wong
    Citation: BMC Rheumatology 2023 7:30
  27. The study aimed to investigate novel biomarkers from the C1q TNF superfamily and evaluate their role in autoimmune inflammatory rheumatic diseases with the goal of identifying an effective biomarker to measure...

    Authors: İ.Merve B. Uçar, Gökhan Sargin, Ayça Tuzcu, Songül Çildağ and Taşkın Şentürk
    Citation: BMC Rheumatology 2023 7:29
  28. To study the risk of osteoporosis-related fractures in a community-based sample of men and women with rheumatoid arthritis (RA) overall, as well as early (< 1 year of disease duration, follow-up time maximum 1...

    Authors: Lisa Theander, Lennart T.H. Jacobsson and Carl Turesson
    Citation: BMC Rheumatology 2023 7:28
  29. Lifestyle physical activity (PA) is defined as any type of PA undertaken as part of daily life. It can include engagement in activities of daily living (i.e., household chores, gardening, walking to work), inc...

    Authors: Sophia M. Brady, Jet J. C. S. Veldhuijzen van Zanten, Petros C. Dinas, Tom E. Nightingale, George S. Metsios, Saleh M. A. Elmsmari, Joan L. Duda, George D. Kitas and Sally A. M. Fenton
    Citation: BMC Rheumatology 2023 7:27
  30. The psychological burden in people with inflammatory arthritis is substantial, yet little is known about the disease-related affect experienced by individuals with axial Spondyloarthritis (axial SpA). The aim ...

    Authors: Nicky Wilson, Jia Liu, Qainat Adamjee, Sonya Di Giorgio, Sophia Steer, Jane Hutton and Heidi Lempp
    Citation: BMC Rheumatology 2023 7:26
  31. Behcet’s disease (BD) is a systemic disease characterized by recurrent oral and genital ulcers. The underlying disease pathway likely involves interleukin (IL)-17 A, a proinflammatory cytokine that is implicat...

    Authors: Frances Sze Kei Sun, Nicole Sau Yan Chiu and Ho Yin Chung
    Citation: BMC Rheumatology 2023 7:25
  32. Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals will de...

    Authors: Jacy T. Zanussi, Juan Zhao, Wei-Qi Wei, Gul Karakoc, Cecilia P. Chung, QiPing Feng, Nancy J. Olsen, C. Michael Stein and Vivian K. Kawai
    Citation: BMC Rheumatology 2023 7:24
  33. Risk of fragility fractures in patients with rheumatoid arthritis (RA) is increased. Disease-related inflammation in RA is associated with low Bone Mineral Density (BMD). However, effects of specific disease f...

    Authors: Sofia Ajeganova, Maria Andersson, Kristina Forslind, Inger Gjertsson, Britt-Marie Nyhäll-Wåhlin, Björn Svensson and Ingiäld Hafström
    Citation: BMC Rheumatology 2023 7:23
  34. We assessed the risk factors and outcome of COVID-19 in patients with autoimmune rheumatic diseases(AIRD) who contracted infection while on background treatment with tofacitinib.

    Authors: Pramod Chebbi, Vineeta Shobha, Vijay K Rao, Vikram Haridas, Ramya Janardana, Benzeeta Pinto, Sharath Kumar, Abhishek Patil, Roopa Tekkatte, Manasa Salanke and K M Mahendranath
    Citation: BMC Rheumatology 2023 7:22
  35. Poor sleep quality is a common and potentially debilitating problem in systemic sclerosis (SSc). To date, no data clarifies the potential factors related to poor sleep quality and the clinical associations wit...

    Authors: Nonthaphorn Wongthawa, Apichart So-gnern, Ajanee Mahakkanukrauh, Siraphop Suwannaroj and Chingching Foocharoen
    Citation: BMC Rheumatology 2023 7:21
  36. The importance of COVID-19 vaccination for patients on immunosuppressive (IS) medication has increased due to the high risk of severe disease or mortality. Different vaccines have varying efficacy rates agains...

    Authors: Fulya Cosan, Ozlem Unay Demirel, Demet Yalcin, Muhammed Mert Sonkaya, Isilsu Ezgi Uluisik, Olida Cecen, Yavuz Furuncuoglu, Deniz Maktav Celikmen, Osman Kara, Erkan Ceylan and Timucin Avsar
    Citation: BMC Rheumatology 2023 7:20
  37. This paper estimates spatial inequalities of Rheumatoid Arthritis (RA) in Colombia and explores correlates of those disparities from a health system perspective.

    Authors: Norman Maldonado, Sandra Camacho, Sergio I. Prada, Andrés Hormaza-Jaramillo, Victoria Soto, William García, Nelcy Paredes and Fabián Cardona
    Citation: BMC Rheumatology 2023 7:19
  38. VEXAS is a recently described inflammatory disease caused by mutations in the UBA1 gene. Symptoms are diverse and include fevers, cartilaginous inflammation, lung inflammation, vasculitis, neutrophilic dermatoses...

    Authors: Khiem T. Vu, Rachel M. Wolfe, Jonathan E. Lambird and Danielle L. V. Maracaja
    Citation: BMC Rheumatology 2023 7:18
  39. Early assessment of patient preferences has the potential to support shared decisions in personalized precision medicine for patients with rheumatoid arthritis (RA). The aim of this study was to assess treatme...

    Authors: Karin Schölin Bywall, Bente Appel Esbensen, Marie Heidenvall, Inger Erlandsson, Marta Lason, Mats Hansson and Jennifer Viberg Johansson
    Citation: BMC Rheumatology 2023 7:17
  40. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease which impacts patients’ lives. Many studies in high-income countries have focused on their health-related quality of life (HRQoL). However, ev...

    Authors: Aya Mizukami, Minh Trang Trinh, Thi Phuong Hoang, Akira Shibanuma, Ken Ing Cherng Ong and Masamine Jimba
    Citation: BMC Rheumatology 2023 7:16
  41. Gout is the most common inflammatory arthritis, increasing in prevalence and burden. Of the rheumatic diseases, gout is the best-understood and potentially most manageable condition. However, it frequently rem...

    Authors: Brooke Conley, Samantha Bunzli, Jonathan Bullen, Penny O’Brien, Jennifer Persaud, Tilini Gunatillake, Michelle M Dowsey, Peter F Choong, Mandana Nikpour, Rebecca Grainger and Ivan Lin
    Citation: BMC Rheumatology 2023 7:15
  42. Air pollution is a key public health factor with the capacity to induce diseases. The risk of ischemia heart disease (IHD) in those suffering from systemic lupus erythematosus (SLE) from air pollution exposure...

    Authors: Pei-Yun Chen, Yu-Tse Tsan, Chao-Tung Yang, Yun-Mei Lee, Li-Li Chen, Wen-Chao Ho and Shu-Hua Lu
    Citation: BMC Rheumatology 2023 7:14
  43. The inability to assess structural changes in facet joints is a limitation of established radiographic scoring systems for ankylosing spondylitis (AS). We compared radiographic evidence of ankylosis in cervica...

    Authors: Tae-Han Lee, Seunghun Lee, Bon San Koo, Kyung Bin Joo and Tae-Hwan Kim
    Citation: BMC Rheumatology 2023 7:11
  44. The novel Coronavirus disease (COVID-19) pandemic has represented an evolving global threat with high morbidity and mortality. Patients with autoimmune rheumatic diseases and on immune-suppressing medications ...

    Authors: Nicole K. Zagelbaum Ward, Suman Pal, Katherine Ruddy and Stavros Savvas
    Citation: BMC Rheumatology 2023 7:13
  45. Patient and public involvement is an idea whose time has firmly come. It is the views of these Guest Editors that it is the right thing to do morally and improves research quality and applicability.

    Authors: Angie Botto-van Bemden, Adewale O. Adebajo and Ciarán Martin Fitzpatrick
    Citation: BMC Rheumatology 2023 7:12
  46. Flare-up of systemic lupus erythematosus (SLE) is a common characteristic that could have deleterious effects on patients’ outcome and survival. The aim of this study was to identify the predictors of severe l...

    Authors: Alimohammad Fatemi, Elaheh Keivani-Boroujeni and Abbas Smiley
    Citation: BMC Rheumatology 2023 7:10
  47. Systemic sclerosis (SSc) is a rare autoimmune disorder characterized by vascular and fibrosing involvement of the skin and internal organs. In this study, we determined the prevalence and characteristics of ra...

    Authors: Fatemeh Badiee, Alireza Fatemi, Reza Zahedpasha, Mohammad Hadi Gharib, Mohammadhassan Jokar, Somayeh Livani, Mehrdad Aghaie and Nafiseh Abdolahi
    Citation: BMC Rheumatology 2023 7:9

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