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Table 4 Multivariable logistic regression analysis for clinically relevant progression (≥ MCID of 5)

From: Radiographic progression in early rheumatoid arthritis patients following initial combination versus step-up treat-to-target therapy in daily clinical practice: results from the DREAM registry

Variable

OR

95% CI

p

Strategy (Initial monotherapy)

3.84

1.16–12.73

0.028

TJC

0.89

0.78–1.00

0.050

SJC

1.07

0.92–1.23

0.393

SJC x Strategy

1.17

0.90–1.51

0.236

ESR

1.03

1.01–1.05

0.015

Anti-CCP positive

1.91

0.66–5.48

0.229

SF-36 PCS

1.04

0.98–1.12

0.202

SF-36 PCS x Strategy

0.87

0.76–0.99

0.034

BMI

0.91

0.81–1.02

0.114

  1. Nagelkerke R-square MCID = 0.266; N = 159
  2. All continuous variables were mean-centered to avoid multicollinearity
  3. TJC tender joint count, SJC swollen joint count, ESR erythrocyte sedimentation rate, Anti-CCP anti-cyclic citrullinated peptide