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Table 4 Multivariable logistic regression analysis for clinically relevant progression (≥ MCID of 5)

From: Radiographic progression in early rheumatoid arthritis patients following initial combination versus step-up treat-to-target therapy in daily clinical practice: results from the DREAM registry

Variable OR 95% CI p
Strategy (Initial monotherapy) 3.84 1.16–12.73 0.028
TJC 0.89 0.78–1.00 0.050
SJC 1.07 0.92–1.23 0.393
SJC x Strategy 1.17 0.90–1.51 0.236
ESR 1.03 1.01–1.05 0.015
Anti-CCP positive 1.91 0.66–5.48 0.229
SF-36 PCS 1.04 0.98–1.12 0.202
SF-36 PCS x Strategy 0.87 0.76–0.99 0.034
BMI 0.91 0.81–1.02 0.114
  1. Nagelkerke R-square MCID = 0.266; N = 159
  2. All continuous variables were mean-centered to avoid multicollinearity
  3. TJC tender joint count, SJC swollen joint count, ESR erythrocyte sedimentation rate, Anti-CCP anti-cyclic citrullinated peptide