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Table 2 Associations of DAS28-related variables with pressure pain thresholds and fibromyalgia classification

From: Interpretation of DAS28 and its components in the assessment of inflammatory and non-inflammatory aspects of rheumatoid arthritis

Index

Medial Tibia PPT

Fibromyalgia (FM) classification

B (95% CI)

p

RA with FM

RA (no FM)

p

Difference

Effect size

TJC

− 0.39 (− 0.63 to − 0.15)

0.002

14 (7)

8 (6)

0.01

5.3

0.75

VAS-GH

− 0.37 (− 0.61 to − 0.13)

0.003

67 (19)

42 (19)

< 0.001

25

1.09

SJC

0.03 (− 0.23 to 0.28)

0.834

1 (1)

1 (2)

0.742

0.15

0.1

ESR

−0.10 (− 0.36 to 0.17)

0.464

23 (16)

20 (11)

0.51

2.7

0.2

DAS28

− 0.53 (− 0.77 to − 0.29)

< 0.001

5.2 (0.8)

4.4 (0.8)

0.001

0.79

0.93

DAS28-P

−0.41 (− 0.62 to − 0.13)

0.003

0.56 (0.11)

0.48 (0.09)

0.008

0.09

0.81

Tender-swollen difference

−0.38 (− 0.62 to − 0.15)

0.002

12 (8)

7 (6)

0.011

5.5

0.76

Tender:swollen ratio

−0.48 (− 0.79 to − 0.18)

0.003

8.4 (7.0)

6.2 (5.9)

0.363

2.1

0.33

  1. Data from PPT study, n = 45. Linear regression between medal tibial pressure pain thresholds (PPT) and DAS28-related variables (lower values of PPTs indicate greater pain sensitivity). Means (sd); T-Tests and Cohens d effect size for differences between patients with RA ± fibromyalgia (FM). TJC tender joint count, SJC swollen joint count, ESR erythrocyte sedimentation rate, VAS-GH visual analogue scale-general health. DAS28-P = proportion of DAS28-ESR attributable to patient-reported components. No corrects were performed for multiple comparisons. Statistically significant findings highlighted in bold