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Table 2 Associations of DAS28-related variables with pressure pain thresholds and fibromyalgia classification

From: Interpretation of DAS28 and its components in the assessment of inflammatory and non-inflammatory aspects of rheumatoid arthritis

Index Medial Tibia PPT Fibromyalgia (FM) classification
B (95% CI) p RA with FM RA (no FM) p Difference Effect size
TJC − 0.39 (− 0.63 to − 0.15) 0.002 14 (7) 8 (6) 0.01 5.3 0.75
VAS-GH − 0.37 (− 0.61 to − 0.13) 0.003 67 (19) 42 (19) < 0.001 25 1.09
SJC 0.03 (− 0.23 to 0.28) 0.834 1 (1) 1 (2) 0.742 0.15 0.1
ESR −0.10 (− 0.36 to 0.17) 0.464 23 (16) 20 (11) 0.51 2.7 0.2
DAS28 − 0.53 (− 0.77 to − 0.29) < 0.001 5.2 (0.8) 4.4 (0.8) 0.001 0.79 0.93
DAS28-P −0.41 (− 0.62 to − 0.13) 0.003 0.56 (0.11) 0.48 (0.09) 0.008 0.09 0.81
Tender-swollen difference −0.38 (− 0.62 to − 0.15) 0.002 12 (8) 7 (6) 0.011 5.5 0.76
Tender:swollen ratio −0.48 (− 0.79 to − 0.18) 0.003 8.4 (7.0) 6.2 (5.9) 0.363 2.1 0.33
  1. Data from PPT study, n = 45. Linear regression between medal tibial pressure pain thresholds (PPT) and DAS28-related variables (lower values of PPTs indicate greater pain sensitivity). Means (sd); T-Tests and Cohens d effect size for differences between patients with RA ± fibromyalgia (FM). TJC tender joint count, SJC swollen joint count, ESR erythrocyte sedimentation rate, VAS-GH visual analogue scale-general health. DAS28-P = proportion of DAS28-ESR attributable to patient-reported components. No corrects were performed for multiple comparisons. Statistically significant findings highlighted in bold