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Table 2 Agreement between different definitions of response and remission

From: Pain, sleep and emotional well-being explain the lack of agreement between physician- and patient-perceived remission in early rheumatoid arthritis

 

Physician-perceived remission

Patient-perceived remission

DAS44 remission

EULAR good response

ACR70 response

Boolean remission

Physician- perceived remission

x

67%

74%

79%

60%

57%

Ƙ = 0.318

Ƙ = 0.439

Ƙ = 0.484

Ƙ = 0.281

Ƙ = 0.248

P = 0.003

P < 0.001

P < 0.001

P = 0.001

P = 0.002

Patient-perceived remission

67%

x

46%

69%

69%

67%

Ƙ = 0.318

Ƙ = 0.516

Ƙ = 0.356

Ƙ = 0.398

Ƙ = 0.354

P = 0.003

P < 0.001

P < 0.001

P < 0.001

P < 0.001

DAS44 remission

74%

46%

x

83%

64%

67%

Ƙ = 0.439

Ƙ = 0.516

Ƙ = 0.622

Ƙ = 0.343

Ƙ = 0.392

P < 0.001

P < 0.001

P < 0.001

P < 0.001

P < 0.001

EULAR good response

79%

69%

83%

x

52%

50%

Ƙ = 0.484

Ƙ = 0.356

Ƙ = 0.622

Ƙ = 0.220

Ƙ = 0.199

P < 0.001

P < 0.001

P < 0.001

P = 0.001

P = 0.002

ACR70 response

60%

69%

64%

52%

x

74%

Ƙ = 0.281

Ƙ = 0.398

Ƙ = 0.343

Ƙ = 0.220

Ƙ = 0.359

P = 0.001

P < 0.001

P < 0.001

P = 0.001

P = 0.001

Boolean remission

57%

67%

67%

50%

74%

x

Ƙ = 0.248

Ƙ = 0.354

Ƙ = 0.392

Ƙ = 0.199

Ƙ = 0.359

P = 0.002

P < 0.001

P < 0.001

P = 0.002

P = 0.001

  1. Numbers are presented as level of agreement (%), kappa value (K) and p-value (P)
  2. Physician-perceived remission was defined as a VAS of ≤10 mm as answer to the question: “How active do you think the rheumatoid arthritis of your patient is today?”
  3. Patient-perceived remission was defined as “yes” or “no” as answer to the question: “Would you say that, at this moment, your disease activity is as good as gone?”
  4. ACR70 American College of Rheumatology 70 response, DAS44 disease activity score of 44 joints, EULAR European League Against Rheumatism, mm millimeter