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Table 2 Agreement between different definitions of response and remission

From: Pain, sleep and emotional well-being explain the lack of agreement between physician- and patient-perceived remission in early rheumatoid arthritis

  Physician-perceived remission Patient-perceived remission DAS44 remission EULAR good response ACR70 response Boolean remission
Physician- perceived remission x 67% 74% 79% 60% 57%
Ƙ = 0.318 Ƙ = 0.439 Ƙ = 0.484 Ƙ = 0.281 Ƙ = 0.248
P = 0.003 P < 0.001 P < 0.001 P = 0.001 P = 0.002
Patient-perceived remission 67% x 46% 69% 69% 67%
Ƙ = 0.318 Ƙ = 0.516 Ƙ = 0.356 Ƙ = 0.398 Ƙ = 0.354
P = 0.003 P < 0.001 P < 0.001 P < 0.001 P < 0.001
DAS44 remission 74% 46% x 83% 64% 67%
Ƙ = 0.439 Ƙ = 0.516 Ƙ = 0.622 Ƙ = 0.343 Ƙ = 0.392
P < 0.001 P < 0.001 P < 0.001 P < 0.001 P < 0.001
EULAR good response 79% 69% 83% x 52% 50%
Ƙ = 0.484 Ƙ = 0.356 Ƙ = 0.622 Ƙ = 0.220 Ƙ = 0.199
P < 0.001 P < 0.001 P < 0.001 P = 0.001 P = 0.002
ACR70 response 60% 69% 64% 52% x 74%
Ƙ = 0.281 Ƙ = 0.398 Ƙ = 0.343 Ƙ = 0.220 Ƙ = 0.359
P = 0.001 P < 0.001 P < 0.001 P = 0.001 P = 0.001
Boolean remission 57% 67% 67% 50% 74% x
Ƙ = 0.248 Ƙ = 0.354 Ƙ = 0.392 Ƙ = 0.199 Ƙ = 0.359
P = 0.002 P < 0.001 P < 0.001 P = 0.002 P = 0.001
  1. Numbers are presented as level of agreement (%), kappa value (K) and p-value (P)
  2. Physician-perceived remission was defined as a VAS of ≤10 mm as answer to the question: “How active do you think the rheumatoid arthritis of your patient is today?”
  3. Patient-perceived remission was defined as “yes” or “no” as answer to the question: “Would you say that, at this moment, your disease activity is as good as gone?”
  4. ACR70 American College of Rheumatology 70 response, DAS44 disease activity score of 44 joints, EULAR European League Against Rheumatism, mm millimeter