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Fig. 5 | BMC Rheumatology

Fig. 5

From: Resveratrol displays anti-inflammatory properties in an ex vivo model of immune mediated inflammatory arthritis

Fig. 5

Ratios of MCP-1 (a, n = 14 and b, n = 8 (RSV and MTX + RSV) or n = 7 (MTX, ADA and ADA + RSV)) and MMP3 (c, n = 9) concentrations, and TRAP activity (d, n = 8) in supernatants from cultures with the noted substance or a combination of resveratrol (RSV), Ebetrex (MTX) and Adalimumab (ADA). Concentrations were: RSV; 25 μM, MTX; 0.5 μg/ml, Adalimumab; 5 μg/ml. MCP-1 and MMP3 were measured by ELISA and TRAP with an enzyme activity assay. Data is presented as a dot for each measurement; box and bars represent median and interquartile range. *p < 0.05 vs. negative control

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