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Table 2 Differences in the exosomal protein profiles among the disease categories detected by 2D-DIGE

From: A proteomic analysis of serum-derived exosomes in rheumatoid arthritis

A. wRA vs. HL
Total number of detected protein spots Number of spots with different intensities (p < 0.05) fold difference (wRA/HL) number of spots
204 28 X ≥ 1.3 5
1.3 > X > −1.3 21
−1.3 ≥ X 2
B. aRA vs. HL
Total number of detected protein spots Number of spots with different intensities (p < 0.05) fold difference (aRA/HL) number of spots
204 31 X ≥ 1.3 13
1.3 > X > −1.3 7
− 1.3 ≥ X 11
C. iRA vs. HL
Total number of detected protein spots Number of spots with different intensities (p < 0.05) fold difference (iRA/HL) number of spots
204 14 X ≥ 1.3 1
1.3 > X > −1.3 9
−1.3 ≥ X 4
D. OA vs. HL
Total number of detected protein spots Number of spots with different intensities (p < 0.05) fold difference (OA/HL) number of spots
204 21 X ≥ 1.3 1
1.3 > X > −1.3 14
−1.3 ≥ X 6
  1. wRA whole RA, aRA active RA, iRA inactive RA, OA osteoarthritis, HL healthy donor