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Table 2 Differences in the exosomal protein profiles among the disease categories detected by 2D-DIGE

From: A proteomic analysis of serum-derived exosomes in rheumatoid arthritis

A. wRA vs. HL

Total number of detected protein spots

Number of spots with different intensities (p < 0.05)

fold difference (wRA/HL)

number of spots

204

28

X ≥ 1.3

5

1.3 > X > −1.3

21

−1.3 ≥ X

2

B. aRA vs. HL

Total number of detected protein spots

Number of spots with different intensities (p < 0.05)

fold difference (aRA/HL)

number of spots

204

31

X ≥ 1.3

13

1.3 > X > −1.3

7

− 1.3 ≥ X

11

C. iRA vs. HL

Total number of detected protein spots

Number of spots with different intensities (p < 0.05)

fold difference (iRA/HL)

number of spots

204

14

X ≥ 1.3

1

1.3 > X > −1.3

9

−1.3 ≥ X

4

D. OA vs. HL

Total number of detected protein spots

Number of spots with different intensities (p < 0.05)

fold difference (OA/HL)

number of spots

204

21

X ≥ 1.3

1

1.3 > X > −1.3

14

−1.3 ≥ X

6

  1. wRA whole RA, aRA active RA, iRA inactive RA, OA osteoarthritis, HL healthy donor