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Table 2 SSc mortality rates, SMR and hazard ratios

From: Trends in incidence, mortality, and causes of death associated with systemic sclerosis in Denmark between 1995 and 2015: a nationwide cohort study

  1-year background mortality rate (per 100 PY) 1-year SSc mortality (no cases) 1-year SSc mortality rate (per 100 PY) 5-year SSc mortality (no cases) 5-mortality mortality rate (per 100 PY) 1-year SMR 1-year hazard ratio compared to background population (age and sex adjusted)
1995 1.23 (1.23–1.23) 8 6.1 (3.1–12.2) 19 3.1 (2.0–4.8) 5.0 5.3 (2.7–10.6)
1996 1.18 (1.17–1.19) ≤3 2.6 (0.8–8.1) 24 4.6 (3.1–6.8) 2.2 2.1 (0.7–6.4)
1997 1.16 (1.15–1.17) 9 8.7 (4.5–16.6) 24 4.9 (3.3–7.4) 7.5 8.3 (4.4–16.0)
1998 1.12 (1.11–1.13) 15 14.5 (8.8–24.1) 20 4.1 (2.6–6.3) 13.0 14.3 (8.6–23.7)
1999 1.13 (1.11–1.14) 8 5.3 (2.6–10.5) 28 4.0 (2.8–5.8) 4.7 5.2 (2.6–10.4)
2000 1.09 (1.08–1.10) 5 4.9 (2.1–11.9) 13 2.7 (1.6–4.7) 4.5 5.3 (2.2–12.6)
2001 1.10 (1.08–1.10) 9 10.5 (5.5–20.2) 23 6.1 (4.0–9.1) 9.6 9.6 (5.0–18.3)
2002 1.10 (1.09–1.10) 10 8.8 (4.8–16.4) 21 4.0 (2.6–6.1) 8.0 7.6 (4.1–14.1)
2003 1.07 (1.06–1.07) 8 6.7 (3.3–13.3) 27 5.0 (3.4–7.2) 6.3 6.5 (3.3–13.0)
2004 1.03 (1.02–1.03) 5 4.9 (2.0–11.8) 12 2.4 (1.4–4.3) 4.8 5.2 (2.2–12.4)
2005 1.00 (0.99–1.01) 7 6.0 (2.9–12.6) 26 4.9 (3.3–7.2) 6 5.6 (2.7–11.8)
2006 1.00 (1.00–1.01) 5 3.7 (1.5–8.9) 16 2.5 (1.5–4.0) 3.7 4.1 (1.7–9.8)
2007 1.00 (0.99–1.00) 7 5.1 (2.5–10.8) 18 2.8 (1.8–4.4) 5.1 6.2 (3.0–13.0)
2008 0.97 (0.96–0.98) 6 4.5 (2.0–10.0) 19 3.0 (1.9–4.7) 4.6 4.7 (2.1–10.4)
2009 0.97 (0.96–0.98) 11 8.1 (4.5–14.6) 23 3.6 (2.4–5.4) 8.4 8.2 (4.5–14.7)
2010 0.95 (0.94–0.96) 4 2.6 (1.0–7.0) 23 3.2 (2.1–4.8) 2.7 2.8 (1.1–7.4)
2011 0.91 (0.91–0.92) 12 7.2 (4.1–12.8) 25 3.2 (2.2–4.7) 7.9 8.9 (5.1–15.8)
2012 0.90 (0.89–0.91) 5 3.6 (1.6–9.5) 22 NA 4.0 4.8 (2.0–11.5)
2013 0.90 (0.89–0.91) 8 5.5 (2.7–11.0) 22 NA 6.1 6.0 (3.0–12.1)
2014 0.88 (0.87–0.89) 4 2.3 (0.9–6.2) 12 NA 2.6 3.0 (1.1–8.0)
2015 0.90 (0.89–9.90) 7 5.3 (2.5–6.2) 10 NA 5.9 5.6 (2.7–11.8)
Overall 1.02 (1.02–1.03) NA 5.8 (5.0–6.8) 427 3.7 (3.3–4.1) 5.7 5.5 (4.7–6.4)
  1. Footnote: SMR denotes standardized mortality rate (i.e., mortality rate in SSc patients divided by mortality rate in background population). Mortality rates and hazard ratio are presented with 95% CIs