TY - STD TI - Shim J, Stavre Z, Gravallese EM. Bone loss in rheumatoid arthritis: basic mechanisms and clinical implications. Calcif Tissue Int. 2018;102(5):533-46. ID - ref1 ER - TY - JOUR AU - Karsdal, M. A. AU - Bay-Jensen, A. -. C. AU - Henriksen, K. AU - Christiansen, C. AU - Genant, H. K. AU - Chamberlain, C. PY - 2014 DA - 2014// TI - Rheumatoid arthritis: a case for personalized health care? JO - Arthritis Care Res (Hoboken) VL - 66 UR - https://doi.org/10.1002/acr.22289 DO - 10.1002/acr.22289 ID - Karsdal2014 ER - TY - JOUR AU - Gay, S. AU - Gay, R. E. AU - Miller, E. J. PY - 1980 DA - 1980// TI - The collagens of the joint JO - Arthritis Rheum John Wiley & Sons, Inc VL - 23 ID - Gay1980 ER - TY - JOUR AU - Cunnane, G. AU - FitzGerald, O. AU - Beeton, C. AU - Cawston, T. E. AU - Bresnihan, B. PY - 2001 DA - 2001// TI - Early joint erosions and serum levels of matrix metalloproteinase 1, metalloproteinase 3 and tissue inhibitor of metalloproteinase 1 in rheunatoid arthritis JO - Arthritis Rheum VL - 44 UR - https://doi.org/3.0.CO;2-1 DO - 3.0.CO;2-1 ID - Cunnane2001 ER - TY - JOUR AU - Konttinen, Y. T. AU - Ainola, M. AU - Valleala, H. AU - Ma, J. AU - Ida, H. AU - Mandelin, J. PY - 1999 DA - 1999// TI - Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis JO - Ann Rheum Dis VL - 55 UR - https://doi.org/10.1136/ard.58.11.691 DO - 10.1136/ard.58.11.691 ID - Konttinen1999 ER - TY - JOUR AU - Kaneko, M. AU - Tomita, T. AU - Nakase, T. AU - Ohsawa, Y. AU - Seki, H. AU - Takeuchi, E. PY - 2001 DA - 2001// TI - Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis JO - Rheumatology VL - 40 UR - https://doi.org/10.1093/rheumatology/40.3.247 DO - 10.1093/rheumatology/40.3.247 ID - Kaneko2001 ER - TY - JOUR AU - Siebuhr, A. S. AU - Wang, J. AU - Karsdal, M. AU - Bay-Jensen, A. -. C. PY - 2012 DA - 2012// TI - Matrix metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis JO - J Transl Med VL - 10 UR - https://doi.org/10.1186/1479-5876-10-195 DO - 10.1186/1479-5876-10-195 ID - Siebuhr2012 ER - TY - STD TI - Kjelgaard-Petersen C, Siebuhr AS, Christiansen T, Ladel C, Karsdal M, Bay-Jensen A-C. Synovitis biomarkers: ex vivo characterization of three biomarkers for identification of inflammatory osteoarthritis. Biomarkers. 2015 [cited 2017 Sep 9];20:547–556. Available from: http://www.tandfonline.com/doi/full/10.3109/1354750X.2015.1105497 UR - http://www.tandfonline.com/doi/full/10.3109/1354750X.2015.1105497 ID - ref8 ER - TY - JOUR AU - Shiozawa, K. AU - Yamane, T. AU - Murata, M. AU - Yoshihara, R. AU - Tsumiyama, K. AU - Imura, S. PY - 2016 DA - 2016// TI - MMP-3 as a predictor for structural remission in RA patients treated with MTX monotherapy. Arthritis res. Ther JO - BioMed Central Ltd VL - 18 ID - Shiozawa2016 ER - TY - STD TI - Siebuhr AS, He Y, Gudmann NS, Gram A, Kjelgaard-Petersen CF, Qvist P, et al. Biomarkers of cartilage and surrounding joint tissue. Biomark. Med. [cited 2018 Jun 13]. 2014;8:713–31. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554760/. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554760/ ID - ref10 ER - TY - JOUR AU - Bay-Jensen, A. C. AU - Platt, A. AU - Byrjalsen, I. AU - Vergnoud, P. AU - Christiansen, C. AU - M a, K. PY - 2014 DA - 2014// TI - Effect of tocilizumab combined with methotrexate on circulating biomarkers of synovium, cartilage, and bone in the LITHE study JO - Semin Arthritis Rheum Elsevier VL - 43 UR - https://doi.org/10.1016/j.semarthrit.2013.07.008 DO - 10.1016/j.semarthrit.2013.07.008 ID - Bay-Jensen2014 ER - TY - JOUR AU - Siebuhr, A. AU - Bay-Jensen, A. C. AU - Leeming, D. J. AU - Plat, A. AU - Byrjalsen, I. AU - Christiansen, C. PY - 2013 DA - 2013// TI - Serological identification of fast progressors of structural damage with rheumatoid arthritis JO - Arthritis Res. Ther. VL - 15 UR - https://doi.org/10.1186/ar4266 DO - 10.1186/ar4266 ID - Siebuhr2013 ER - TY - STD TI - Maijer KI, Gudmann NS, Karsdal MA, Gerlag DM, Tak PP, Bay-Jensen AC. Neo-epitopes--fragments of cartilage and connective tissue degradation in early rheumatoid arthritis and unclassified arthritis. Pietropaolo M, editor. PLoS One. [cited 2018 Jun 13]. 2016;11:e0149329. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809616/. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809616/ ID - ref13 ER - TY - JOUR AU - Aletaha, D. AU - Alasti, F. AU - Smolen, J. S. PY - 2013 DA - 2013// TI - Rheumatoid factor determines structural progression of rheumatoid arthritis dependent and independent of disease activity JO - Ann.Rheum.Dis VL - 72 UR - https://doi.org/10.1136/annrheumdis-2012-201517 DO - 10.1136/annrheumdis-2012-201517 ID - Aletaha2013 ER - TY - STD TI - Jansen LM, van der Horst-Bruinsma IE, van Schaardenburg D, Bezemer PD, Dijkmans BA. Predictors of radiographic joint damage in patients with early rheumatoid arthritis. Ann. Rheum. Dis. [cited 2018 mar 13]. 2001;60:924–7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1753390/. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1753390/ ID - ref15 ER - TY - JOUR AU - Genovese, M. C. AU - Heijde, D. M. AU - Keystone, E. C. AU - Spindler, A. J. AU - Benhamou, C. AU - Kavanaugh, A. PY - 2014 DA - 2014// TI - A phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of 2 dosing regimens of fostamatinib in patients with rheumatoid arthritis with an inadequate response to a tumor necrosis factor-α antagonist JO - J Rheumatol VL - 41 UR - https://doi.org/10.3899/jrheum.140238 DO - 10.3899/jrheum.140238 ID - Genovese2014 ER - TY - STD TI - Weinblatt ME, Genovese MC, Ho M, Hollis S, Rosiak-Jedrychowicz K, Kavanaugh A, et al. Effects of Fostamatinib, an Oral Spleen Tyrosine Kinase Inhibitor, in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate: Results From a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study. Arthritis Rheumatol. 2014 [cited 2018 Jul 17]; 66: 3255–3264. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25223724. UR - http://www.ncbi.nlm.nih.gov/pubmed/25223724 ID - ref17 ER - TY - JOUR AU - Heijde, D. AU - Simon, L. AU - Smolen, J. AU - Strand, V. AU - Sharp, J. AU - Boers, M. PY - 2002 DA - 2002// TI - How to report radiographic data in randomized clinical trials in rheumatoid arthritis: guidelines from a roundtable discussion JO - Arthritis Rheum VL - 47 UR - https://doi.org/10.1002/art.10181 DO - 10.1002/art.10181 ID - Heijde2002 ER - TY - STD TI - Vastesaeger N, Xu S, Aletaha D, St Clair EW, Smolen JS. A pilot risk model for the prediction of rapid radiographic progression in rheumatoid arthritis. Rheumatology. [cited 2018 Mar 13]. 2009;48:1114–21. Available from: http://www.jrheum.org/content/40/4/369.long. UR - http://www.jrheum.org/content/40/4/369.long ID - ref19 ER - TY - JOUR AU - Wang, S. X. AU - Abramson, S. B. AU - Attur, M. AU - Karsdal, M. A. AU - Preston, R. A. AU - Lozada, C. J. PY - 2017 DA - 2017// TI - Safety, tolerability, and pharmacodynamics of an anti-interleukin-1α/β dual variable domain immunoglobulin in patients with osteoarthritis of the knee: a randomized phase 1 study JO - Osteoarthr Cartil VL - 25 UR - https://doi.org/10.1016/j.joca.2017.09.007 DO - 10.1016/j.joca.2017.09.007 ID - Wang2017 ER - TY - STD TI - Guo X, Higgs BW, Bay-Jensen A-C, Wu Y, Karsdal MA, Kuziora M, et al. Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis. Rheumatology (Oxford). 2018 [cited 2018 Jun 13];57:175–184. Available from: http://academic.oup.com/rheumatology/article/57/1/175/4562458 ID - ref21 ER - TY - JOUR AU - Scott, D. L. AU - Houssien, D. A. PY - 1996 DA - 1996// TI - Clinical and laboratory assessments in rheumatoid arthritis and osteoarthritis JO - Br J Rheumatol VL - 35 UR - https://doi.org/10.1093/rheumatology/35.suppl_3.6 DO - 10.1093/rheumatology/35.suppl_3.6 ID - Scott1996 ER - TY - STD TI - Otterness IG. The value of C-reactive protein measurement in rheumatoid arthritis. Semin. Arthritis Rheum. [cited 2018 mar 30]. 1994;24:91–104. Available from: https://www.ncbi.nlm.nih.gov/pubmed/7839158. UR - https://www.ncbi.nlm.nih.gov/pubmed/7839158 ID - ref23 ER - TY - JOUR AU - Aletaha, D. AU - Neogi, T. AU - Silman, A. J. AU - Funovits, J. AU - Felson, D. T. AU - Bingham, C. O. PY - 2010 DA - 2010// TI - 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European league against rheumatism collaborative initiative JO - ARTHRITIS Rheum VL - 62 UR - https://doi.org/10.1002/art.27584 DO - 10.1002/art.27584 ID - Aletaha2010 ER - TY - JOUR AU - Siebuhr, A. S. AU - Bay-Jensen, A. C. AU - Karsdal, M. A. AU - Lories, R. J. AU - Vlam, K. PY - 2016 DA - 2016// TI - CRP and a biomarker of type i collagen degradation, C1M, can differentiate anti-inflammatory treatment response in ankylosing spondylitis JO - Biomark Med VL - 10 UR - https://doi.org/10.2217/bmm.15.119 DO - 10.2217/bmm.15.119 ID - Siebuhr2016 ER - TY - JOUR AU - Bay-Jensen, A. C. AU - Byrjalsen, I. AU - Siebuhr, A. S. AU - Christiansen, C. AU - Platt, A. AU - Karsdal, M. A. PY - 2014 DA - 2014// TI - Serological biomarkers of joint tissue turnover predict tocilizumab response at baseline JO - J Clin Rheumatol VL - 20 ID - Bay-Jensen2014 ER - TY - JOUR AU - Radojčić, M. R. AU - Thudium, C. S. AU - Henriksen, K. AU - Tan, K. AU - Karlsten, R. AU - Dudley, A. PY - 2017 DA - 2017// TI - Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients JO - Pain VL - 158 UR - https://doi.org/10.1097/j.pain.0000000000000908 DO - 10.1097/j.pain.0000000000000908 ID - Radojčić2017 ER - TY - JOUR AU - Bay-Jensen, A. C. AU - Platt, A. AU - Siebuhr, A. S. AU - Christiansen, C. AU - Byrjalsen, I. AU - Karsdal, M. A. PY - 2016 DA - 2016// TI - Early changes in blood-based joint tissue destruction biomarkers are predictive of response to tocilizumab in the LITHE study JO - Arthritis Res Ther VL - 18 UR - https://doi.org/10.1186/s13075-015-0913-x DO - 10.1186/s13075-015-0913-x ID - Bay-Jensen2016 ER -