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Table 5 Biomarker levels at baseline in escape and non-escape patients. Patients with inadequate response to the therapy went to escape at week 12. The levels and proportions were compared by Mann-Whitney testa or Chi-squared testb

From: Tissue metabolite of type I collagen, C1M, and CRP predicts structural progression of rheumatoid arthritis

Variable Escape patients Non-escape patients
Mean (SD) n No biomarker high and very high patients (%) Mean (SD) Pa n No biomarker high and very high patients (%) Pb
C1M 119 (93) 181 102 (56%)
57 (32%)
93 (69) 0.0019 293 135 (46%)
61 (21%)
0.030
0.0091
C3M 35.2 (15.3) 181 93 (51%)
52 (29%)
33.4 (14.7) > 0.1 293 144 (49%)
66 (23%)
> 0.1
> 0.1
RF 233 (362) 181 141 (78%)
79 (44%)
227 (422) > 0.1 293 239 (82%)
118 (40%)
> 0.1
> 0.1
CRP 20.4 (26.2) 181 102 (56%)
61 (34%)
12.6 (16.6) 0.0009 293 132 (45%)
57 (20%)
0.017
0.0001