Table 5 Biomarker levels at baseline in escape and non-escape patients. Patients with inadequate response to the therapy went to escape at week 12. The levels and proportions were compared by Mann-Whitney testa or Chi-squared testb
Variable | Escape patients | Non-escape patients | ||||||
|---|---|---|---|---|---|---|---|---|
Mean (SD) | n | No biomarker high and very high patients (%) | Mean (SD) | Pa | n | No biomarker high and very high patients (%) | Pb | |
C1M | 119 (93) | 181 | 102 (56%) 57 (32%) | 93 (69) | 0.0019 | 293 | 135 (46%) 61 (21%) | 0.030 0.0091 |
C3M | 35.2 (15.3) | 181 | 93 (51%) 52 (29%) | 33.4 (14.7) | > 0.1 | 293 | 144 (49%) 66 (23%) | > 0.1 > 0.1 |
RF | 233 (362) | 181 | 141 (78%) 79 (44%) | 227 (422) | > 0.1 | 293 | 239 (82%) 118 (40%) | > 0.1 > 0.1 |
CRP | 20.4 (26.2) | 181 | 102 (56%) 61 (34%) | 12.6 (16.6) | 0.0009 | 293 | 132 (45%) 57 (20%) | 0.017 0.0001 |