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Table 4 Characteristics of AOSD patients with initially active disease and follow up at first and last visit

From: Comparative study of Interleukin-18 (IL-18) serum levels in adult onset Still’s disease (AOSD) and systemic onset juvenile idiopathic arthritis (sJIA) and its use as a biomarker for diagnosis and evaluation of disease activity

Parameter First IL-18 determination Last IL-18 determination
Number 11 11
Age in years (SD; Range) 38 (±16.0; 19–63) 40.4 (±16.0; 20–64)
Time after first IL-18 determination in months (SD; Range) 0 27.5 (±26.4; 3–67)
Rau Score (SD; Range) 4.18 (±1.47; 2–6) 0.36 (±67; 0–2)
CRP mg/l (SD; Range) 104.4 (±68.4; 16.2–208) 7.8 (±8.3; < 5–32.7)
ESR mm/1 h (SD; Range) 51 (±23; 11–82) 14.5 (±13.4; 2–47)
IL-18 pg/ml (Range)* 12,500 (850–408,000) 402 (20–7560)
WBC Gpt/ml (SD; Range) 15.0 (± 11.6; 5.4–46.5) 7.3 (± 1.78; 4.9–9.7)
  1. *Median; SD Standard Deviation, CRP C-reactive protein, ESR erythrocyte sedimentation rate, WBC white blood cell count