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Table 4 Methodological quality of the non-RCTs as per CASP checklist

From: Relapse rates after elective discontinuation of anti-TNF therapy in rheumatoid arthritis: a meta-analysis and review of literature

Sl

Study Name

Clearly focused issue

Recruitment acceptable

Exposure measured accurately

Outcome measured accurately

Identified all confounders

Confounders accounted for

Follow-up complete

Follow up long enough

1

Nawata et al., 2008

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

2

Brocq et al., 2009

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

3

Tanaka et al., 2010

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

4

van den Broek et al., 2011

Yes

Yes

Yes

Yes

Yes

Yes

Cannot tell

Yes

5

van den Massk et al., 2012

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

6

Harigai et al., 2012

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

7

Hirata et al., 2013

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

8

Iwamoto et al., 2014

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

9

Kádár et al., 2014

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

10

Tanaka et al., 2015

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

11

NCT00808509 (ADMIRE)

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

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BMC Rheumatology

ISSN: 2520-1026

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