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Table 4 Methodological quality of the non-RCTs as per CASP checklist

From: Relapse rates after elective discontinuation of anti-TNF therapy in rheumatoid arthritis: a meta-analysis and review of literature

Sl Study Name Clearly focused issue Recruitment acceptable Exposure measured accurately Outcome measured accurately Identified all confounders Confounders accounted for Follow-up complete Follow up long enough
1 Nawata et al., 2008 Yes Yes Yes Yes Yes Yes Yes Yes
2 Brocq et al., 2009 Yes Yes Yes Yes Yes Yes Yes Yes
3 Tanaka et al., 2010 Yes Yes Yes Yes Yes Yes Yes Yes
4 van den Broek et al., 2011 Yes Yes Yes Yes Yes Yes Cannot tell Yes
5 van den Massk et al., 2012 Yes Yes Yes Yes Yes Yes Yes Yes
6 Harigai et al., 2012 Yes Yes Yes Yes Yes Yes Yes Yes
7 Hirata et al., 2013 Yes Yes Yes Yes Yes Yes Yes Yes
8 Iwamoto et al., 2014 Yes Yes Yes Yes Yes Yes Yes Yes
9 Kádár et al., 2014 Yes Yes Yes Yes Yes Yes Yes Yes
10 Tanaka et al., 2015 Yes Yes Yes Yes Yes Yes Yes Yes
11 NCT00808509 (ADMIRE) Yes Yes Yes Yes Yes Yes Yes Yes