From: Incident gout and chronic Kidney Disease: healthcare utilization and survival
 | All gout patients | Gout patients without CKD | Gout patients with CKD | p-valuec |
---|---|---|---|---|
Total | 12,940 | 8286 | 4654 | Â |
Died during follow-up, n (%) | 3421 (26.4%) | 1110 (13.4%) | 2311 (49.7%) | < 0.001 |
Person-years | 57,206 | 39,014 | 18,192 | Â |
Age (years) | ||||
 Mean ± SD | 63.8 ± 15.6 | 58.1 ± 14.7 | 74.0 ± 11.3 | < 0.001 |
 IQR 25–75 | 53–76 | 48–69 | 68–82 |  |
Age, n (%) |  |  |  | < 0.001 |
 25–34 years | 621 (4.8%) | 590 (7.1%) | 31 (0.7%) |  |
 35–44 years | 992 (7.7%) | 940 (11.3%) | 52 (1.1%) |  |
 45–54 years | 1924 (14.9%) | 1740 (21.0%) | 184 (4.0%) |  |
 55–64 years | 2799 (21.6%) | 2210 (26.7%) | 589 (12.7%) |  |
 65–74 years | 2917 (22.5%) | 1637 (19.8%) | 1280 (27.5%) |  |
 75–84 years | 2739 (21.2%) | 946 (11.4%) | 1793 (38.5%) |  |
 85+ years | 948 (7.3%) | 223 (2.7%) | 725 (15.6%) |  |
Sex, n (%) |  |  |  | < 0.001 |
 Male | 9819 (75.9%) | 6634 (80.1%) | 3185 (68.4%) |  |
 Female | 3121 (24.1%) | 1652 (19.9%) | 1469 (31.6%) |  |
Socio-economic status, n (%) |  |  |  | < 0.001 |
 Low | 2495 (19.3%) | 1728 (20.9%) | 767 (16.5%) |  |
 Medium | 5717 (44.2%) | 3582 (43.2%) | 2135 (45.9%) |  |
 High | 4651 (35.9%) | 2913 (35.1%) | 1738 (37.3%) |  |
 Missing | 77 (0.6%) | 63 (0.8%) | 14 (0.3%) |  |
Smoking habits, n (%) |  |  |  | < 0.001 |
 Never smoker | 7652 (59.1%) | 4818 (58.2%) | 2834 (60.9%) |  |
 Former smoker | 3346 (25.9%) | 2025 (24.4%) | 1321 (28.4%) |  |
 Current | 1628 (12.6%) | 1313 (15.8%) | 315 (6.8%) |  |
 Missing | 314 (2.4%) | 130 (1.6%) | 184 (4.0%) |  |
BMI (kg/m2), n (%) |  |  |  | < 0.001 |
 Underweight | 60 (0.5%) | 35 (0.4%) | 25 (0.5%) |  |
 Normal | 2013 (15.6%) | 1095 (13.2%) | 918 (19.7%) |  |
 Overweight | 4794 (37.0%) | 3097 (37.4%) | 1697 (36.5%) |  |
 Obese | 5559 (43.0%) | 3755 (45.3%) | 1804 (38.8%) |  |
 Missing | 514 (4.0%) | 304 (3.7%) | 210 (4.5%) |  |
Comorbid condition at index date, n (%) | ||||
 CVD | 4968 (38.4%) | 2070 (25.0%) | 2898 (62.3%) | < 0.001 |
 Diabetes | 3743 (28.9%) | 1883 (22.7%) | 1860 (40.0%) | < 0.001 |
 Hypertension | 8494 (65.6%) | 4367 (52.7%) | 4127 (88.7%) | < 0.001 |
 Cancer | 1571 (12.1%) | 696 (8.4%) | 875 (18.8%) | < 0.001 |
CCI | ||||
 Mean ± SD | 2.1 ± 2.3 | 1.2 ± 1.5 | 3.6 ± 2.7 | < 0.001 |
 IQR 25–75 | 0–3 | 0–2 | 2–5 |  |
CCI, n (%) |  |  |  | < 0.001 |
 0 | 3987 (30.9%) | 3473 (42.0%) | 513 (11.0%) |  |
 1 | 2985 (23.1%) | 2376 (28.7%) | 609 (13.1%) |  |
 2 | 1853 (14.3%) | 1168 (14.1%) | 685 (14.7%) |  |
 3 | 1300 (10.1%) | 602 (7.3%) | 698 (15.0%) |  |
 4 | 906 (7.0%) | 305 (3.7%) | 601 (12.9%) |  |
 5 | 648 (5.0%) | 174 (2.1%) | 474 (10.2%) |  |
 6 | 477 (3.7%) | 94 (1.1%) | 383 (8.2%) |  |
 7+ | 767 (5.9%) | 78 (0.9%) | 689 (14.8%) |  |
 Missing | 17 (0.1%) | 16 (0.2%) | 2 (0.0%) |  |
sUA levels (mg/dL) | ||||
 Mean ± SD | 8.1 ± 2.0 | 7.6 ± 1.7 | 8.9 ± 2.1 | < 0.001 |
 IQR25–75 | 6.8–9.3 | 6.4–8.7 | 7.5–10.1 |  |
sUA levels (mg/dL) |  |  |  | < 0.001 |
  ≤ 6 | 1343 (10.4%) | 981 (11.8%) | 362 (7.8%) |  |
  > 6 | 7796 (60.2%) | 4175 (50.4%) | 3621 (77.8%) |  |
 Missing | 3801 (29.4%) | 3130 (37.8%) | 671 (14.4%) |  |
Gout medicationb, n (%) | 4068 (31.4%) | 2245 (27.1%) | 1823 (39.2%) | < 0.001 |