Fig. 1

Photographs of case 1, demonstrating localized moderate chronic periodontitis a before (baseline) and b after 3 months (reassessment) of tofacitinib therapy. Improvements were observed in the gingival index (GI), probing depth (PD), and clinical attachment level (CAL) at the periodontitis-affected site with the black arrow at b (reassessment) compared to those at a (baseline), although the supragingival bacterial plaque level as defined by the plaque control record (PCR) was relatively unchanged (baseline to reassessment: 2 to 0 for GI; 4 mm to 2 mm for both PD and CAL)