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Table 5 Sensitivity, specificity, positive predictive value, negative predictive value, positive and negative likelihood ratio in different scenarios of the ASAS axSpA criteria in the diagnosis of axSpA

From: Fatty corner lesions in T1-weighted magnetic resonance imaging as an alternative to sacroiliitis for diagnosis of axial spondyloarthritis

  Sensitivity (%) Specificity (%) PPV (%) NPV (%) LR+ LR-
ASAS axSpA criteria (unaltered) 90.3 93.5 90.3 93.5 13.89 0.10
Imaging arm only 84.5 95.2 89.5 95.2 17.60 0.16
Sacroiliitis replaced by ≥3 anterior thoracic FCLs 80.6 93.4 98.0 55.3 12.2 0.21
Sacroiliitis replaced by ≥5 anterior whole spine FCLs 79.4 93.4 97.9 53.8 12.0 0.22
Sacroiliitis or ≥ 3 anterior thoracic FCLs 92.0 93.5 92.0 93.5 14.15 0.09
Sacroiliitis or ≥ 5 anterior whole spine FCLs 91.6 91.9 91.6 91.9 11.31 0.09
  1. PPV positive predictive value, NPV negative predictive value, LR + positive likelihood ratio, LR- negative likelihood ratio, ASAS Assessment of SpondyloArthritis international Society, axSpA axial spondyloarthritis, FCL fatty corner lesion