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Table 1 Demographic and clinical characteristics of the OA phenotypes in MUST

From: Biomarkers of cardiovascular risk across phenotypes of osteoarthritis

  Number with variable Hand OA
n = 154
Lower-Limb OA
n = 111
General OA
n = 100
p
Hand vs Lower-limb
p
Lower-limb vs. Gen. OA
p
Hand vs Gen. OA
Age, mean (range) 366 62.1 (42.0–75.0) 62.9 (45.0–75.0) 64.3 (47.0–75.0) 0.40 0.18 0.02
Female gender, n (%) 366 126 (81.3) 62 (55.9) 76 (76.0) < 0.001 0.002 0.31
Smoking daily, n (%) 363 18 (11.7) 13 (11.9) 12 (12.0) 0.95 0.99 0.94
Higher education, n (%) 359 37 (24.5) 41 (37.3) 26 (26.5) 0.03 0.10 0.72
BMI kg/m2, mean (SD) 356 25.8 (4.3) 28.0 (4.7) 28.1 (4.7) < 0.001 0.77 < 0.001
CRP mg/L, mean (SD) 364 2.2 (3.5) 2.6 (4.4) 2.9 (3.8) 0.44 0.64 0.17
Use of NSAIDs daily
n (%)
364 27 (17.4) 20 (18.2) 20 (20.2) 0.87 0.71 0.58
Heart rate, beats/min (SD) 258 64.4 (10.4) 63.7 (9.8) 65.4 (10.7) 0.63 0.29 0.56
MHAQ 366 1.20 (1.16–1.25) 1.20 (1.15–1.25) 1.26 (1.19–1.32) 0.98 0.19 0.16
Regular exercise n (%) 365 137 (77.4) 101 (91.0) 87 (87.9) 0.50 0.46 0.90
AIx,% mean (SD 258 32.3 (8.5) 29.0 (8.9) 31.7 (8.6) 0.01 0.05 0.67
PWV m/s, mean (SD) 257 8.65 (2.0) 8.7 (1.9) 9.1 (2.0) 0.61 0.25 0.11
ABI 174 1.2 (0.1) 1.2 (0.1) 1.2 (0.2) 0.02 0.46 0.14
  1. Unadjusted bivariate models. The Chi square, independent samples Student T-test or independent samples
  2. Mann-Whitney U-test were used as appropriate
  3. N number, BMI body mass index, CRP C-reactive protein, NSAIDs non-steroidal anti-inflammatory drugs, AIx augmentation index, PWV pulse wave velocity, BP blood pressure. MUST-OA persons in MUST with osteoarthritis, OCP Oslo community controls, UKPC UK population controls