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Table 3 Impact of anxiety/depression in patients with RA

From: The multifaceted impact of anxiety and depression on patients with rheumatoid arthritis

  Overall, N = 1015 No self-reported anxiety/depression, n = 625 Self-reported anxiety/depression, n = 390 P-value (atest)
Clinical measures
 Current flare status, n (%)
  No 860 (86.9) 553 (90.7) 307 (80.8)  
  Yes 130 (13.1) 57 (9.3) 73 (19.2) <.001 (FE)
  bMissing, n 25 15 10  
 DAS28-ESR
  Mean score (SD) 3.6 (1.4) 3.4 (1.3) 4.0 (1.5) <.001 (MW)
  bMissing, n 348 215 133  
 Current disease progression, n (%)
  Unstable/deteriorating 167 (16.9) 60 (9.8) 107 (28.2)  
  Stable 523 (52.8) 339 (55.6) 184 (48.4)  
 Improving 300 (30.3) 211 (34.6) 89 (23.4) <.001 (PC)
bMissing, n 25 15 10  
Is patient currently in remission?, n (%)
  No 503 (49.6) 269 (43.0) 234 (60.0)  
  Yes 512 (50.4) 356 (57.0) 156 (40.0) <.001 (FE)
Employment and impairment
 Patient’s employment status, n (%)
  Unemployed 553 (55.8) 301 (49.1) 252 (66.7)  
  Employed 438 (44.2) 312 (50.9) 126 (33.3) <.001 (FE)
  bMissing, n 24 12 12  
 Percent overall work impairment due to problem (range 0–100)
  Mean (SD) 23.3 (24.4) 18.3 (21.7) 37.5 (26.3) <.001 (MW)
  bMissing, n 684 380 304  
 Percent activity impairment due to problem (range 0–100)
  Mean (SD) 33.4 (25.8) 25.0 (22.4) 47.1 (25.1) <.001 (MW)
  bMissing, n 78 44 34  
cRetired/unemployed due to condition, n (%)
  Not due to RA 92 (68.7) 46 (80.7) 46 (59.7)  
  Due to RA 42 (31.3) 11 (19.3) 31 (40.3) .014 (FE)
  bMissing, n 881 568 313  
 Ever changed job due to condition?, n (%)
  No 804 (90.1) 527 (93.4) 277 (84.5)  
  Yes 88 (9.9) 37 (6.6) 51 (15.5) <.001 (FE)
  bMissing, n 123 61 62  
Disability
 HAQ-DI
  mean HAQ-DI score (SD) 0.8 (0.7) 0.6 (0.6) 1.1 (0.7) <.001 (MW)
  bMissing, n 44 24 20  
  1. DAS28-ESR disease activity score-28 joint count–erythrocyte sedimentation rate; FE Fisher’s exact test; HAQ-DI Health Assessment Questionnaire Disability Index; MW Mann-Whitney’s U test; PC Pearso n’s chi-squared; RA rheumatoid arthritis; SD, standard deviation
  2. aIndicates statistical test performed
  3. bNumber of patients for whom data were not reported
  4. cFor patients who retired below the retirement age of 65 years. Data available only from patients who initially responded as being retired or unemployed