Ustekinumab | TNF inhibitorsa | Infliximab | Etanercept | Adalimumab | Non-biologic/MTXb | Non-biologic/non-MTXc | Alld | |
---|---|---|---|---|---|---|---|---|
Overall population | ||||||||
N | 628 | 1413 | 258 | 481 | 674 | 98 | 208 | 2401 |
PY | 2009 | 4101 | 756 | 1432 | 1913 | 366 | 694 | 7244 |
Serious infections and infestations | 1.00 [20] | 2.22 [91] | 2.12 [16] | 2.58 [37] | 1.99 [38] | 3.01 [11] | 2.31 [16] | 1.91 [138] |
Incident population | ||||||||
N | 326 | 486 | 64 | 130 | 292 | 98 | 208 | 1163 |
PY | 904 | 1082 | 125 | 291 | 665 | 366 | 694 | 3101 |
Serious infections and infestations | 0.88 [8] | 2.50 [27] | 0.80 [1] | 3.09 [9] | 2.56 [17] | 3.01 [11] | 2.31 [16] | 2.00 [62] |
Bionaive population | ||||||||
N | 56 | 167 | 14 | 72 | 81 | 98 | 208 | 532 |
PY | 144 | 419 | 35 | 180 | 204 | 366 | 694 | 1626 |
Serious infections and infestations | 1.39 [2] | 1.91 [8] | 0.00 [0] | 3.33 [6] | 0.98 [2] | 3.01 [11] | 2.31 [16] | 2.28 [37] |