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Fig. 3 | BMC Rheumatology

Fig. 3

From: Serum levels of reactive oxygen metabolites at 12 weeks during tocilizumab therapy are predictive of 52 weeks-disease activity score-remission in patients with rheumatoid arthritis

Fig. 3

ROC curves for ROM (blue), CRP (green), and MMP-3, and cut-off value for ROM that distinguishes DAS-remission from non-remission at 52 weeks. The ROC curves refer to the values at 12 weeks. The cut-off value for ROC curves was determined by the maximum of a Youden index. An asterisk shows the cut-off value for ROM (=305.5). ROC: receiver operating characteristic; ROM: reactive oxygen metabolites; CRP: C-reactive protein; MMP-3: matrix metalloproteinase-3

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