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Table. 3 DAS28 Flare subgroups and their characteristics at the visit before that at which they satisfied flare criteria

From: Disease activity flares and pain flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae

 Moderate DAS28 Flare (n = 171)Self-report DAS28 flare (n = 31)Observed DAS28 flare (n = 34)pPairwise comparisons
MvSRMvOSRvO
DAS282.6 (1.1)3.2 (1.3)4.0 (1.1)< 0.0010.013< 0.0010.017
ESR16 (13)26 (20)22 (17)0.0010.0030.0860.965
SJC1 (2)1 (3)3 (4)0.0060.9990.0040.142
TJC2 (4)3 (4)5 (4)< 0.0010.348< 0.0010.196
VAS24 (18)20 (16)45 (28)< 0.0010.949< 0.001< 0.001
BP40 (11)42 (12)33 (11)0.0010.9990.0020.005
VT46 (11)50 (9)36 (12)< 0.0010.113< 0.001< 0.001
MH50 (10)52 (10)44 (11)0.0050.9990.0090.012
HAQ0.8 (0.8)0.9 (0.8)1.4 (0.9)< 0.0010.999< 0.0010.030
  1. Data are mean (sd) of characteristics at the visit before flare criteria were satisfied. Significant heterogeneity between latent classes at the time point before flare categorisation was recorded after univariate ANOVA. Pairwise comparisons with p values (shown after Bonferonni corrections) were performed. ESR erythrocyte sedimentation rate, SJC swollen joint count, TJC tender joint count, VAS visual analogue scale for general health, BP SF36-Bodily Pain, VT SF36-Vitality, MH SF36-Mental Health. SF36 scores 50 indicate predicted population means, with lower scores indicating greater health impairment. MvSR Moderate vs Self-report, MvO Moderate vs Observed. SRvO Self-report vs Observed. Bold indicates the values for the most severely affected subgroups when heterogeneity was detected