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Table 2 Clinical characteristics of respondents with PsA, stratified by time between seeking medical attention and receiving formal diagnosis

From: Patient perspectives on the pathway to psoriatic arthritis diagnosis: results from a web-based survey of patients in the United States

Characteristics

Total Respondents

(N = 203)

<  6 Months

(n = 69)

6 Months to 4 Years

(n = 68)

≥ 5 Years

(n = 66)

P Value

RAPID3 cumulative score (0–30)

 Mean (SD)

14.7 (5.8)

14.3 (6.5)

14.5 (5.8)

15.4 (5.0)

0.559

 Median (IQR)

15.5 (8.5)

14.5 (10.2)

15.5 (8.9)

16.3 (6.0)

 

 Range

1.3–29.0

1.3–29.0

2.0–24.3

2.0–25.2

 

RAPID3 disease severity category, n (%)

    

0.688

 Near remission (1–3)

5 (2.5)

2 (2.9)

2 (2.9)

1 (1.5)

 

 Low (4–6)

14 (6.9)

6 (8.7)

5 (7.4)

3 (4.5)

 

 Medium (7–12)

45 (22.2)

18 (26.1)

16 (23.5)

11 (16.7)

 

 High (13–30)

139 (68.5)

43 (62.3)

45 (66.2)

51 (77.3)

 

Years since first symptom experienced

 Mean (SD)a

15.1 (11.8)

13.4 (13.2)

10.7 (7.6)

21.3 (11.5)

< 0.001

 Median (IQR)

12.0 (13.0)

8.0 (13.0)

9.0 (10.0)

18.0 (18.0)

 

 Range

0–60.0

0–60.0

1.0–39.0

3.0–52.0

 

Years since official diagnosis

 Mean (SD)

8.7 (9.6)

10.8 (12.4)

8.1 (7.3)

7.3 (7.9)

0.073

 Median (IQR)

6.0 (10.0)

7.0 (11.0)

6.5 (9.0)

5.0 (8.0)

 

 Range

0–60.0

0–60.0

0–39.0

0–42.0

 

Extent of psoriasis (assessed by area covered in number of palms), n (%)b

    

0.259

 Little to no psoriasis (< 1 palm)

105 (51.7)

33 (47.8)

43 (63.2)

29 (43.9)

 

 Only a few patches (1–2 palms)

45 (22.2)

14 (20.3)

12 (17.6)

19 (28.8)

 

 Scattered patches (3–10 palms)

41 (20.2)

17 (24.6)

9 (13.2)

15 (22.7)

 

 Extensive psoriasis (> 10 palms)

12 (5.9)

5 (7.2)

4 (5.9)

3 (4.5)

 

Current symptoms (in ≥ 50% of respondents), n (%)c

 Joint pain

176 (86.7)

57 (82.6)

61 (89.7)

58 (87.9)

0.498

 Fatigue

169 (83.3)

56 (81.2)

57 (83.8)

56 (84.8)

0.867

 Stiffness

159 (78.3)

53 (76.8)

51 (75.0)

55 (83.3)

0.456

 Swollen joints

127 (62.6)

42 (60.9)

45 (66.2)

40 (60.6)

0.759

 Reduced range of motion in the joints of the arms and legs

122 (60.1)

43 (62.3)

38 (55.9)

41 (62.1)

0.679

 Back pain

119 (58.6)

39 (56.5)

37 (54.4)

43 (65.2)

0.414

 Foot problems

115 (56.7)

34 (49.3)

37 (54.4)

44 (66.7)

0.115

 Tendon or ligament paina

109 (53.7)

27 (39.1)

37 (54.4)

45 (68.2)

0.003

 Difficulty walking

108 (53.2)

39 (56.5)

33 (48.5)

36 (54.5)

0.615

 Reduced range of motion in spine and/or hips

107 (52.7)

34 (49.3)

34 (50.0)

39 (59.1)

0.459

Other health conditions (in ≥ 25% of respondents), n (%)c

 Depression

126 (62.1)

35 (55.1)

49 (72.1)

39 (59.1)

0.105

 Anxiety

118 (58.1)

38 (55.1)

40 (58.8)

40 (60.6)

0.806

 Hypertension

97 (47.8)

39 (56.5)

28 (41.2)

30 (45.5)

0.178

 Migraines

90 (44.3)

24 (34.8)

34 (50.0)

32 (48.5)

0.142

 Fibromyalgiaa

77 (37.9)

18 (26.1)

30 (44.1)

29 (43.9)

0.043

 Irritable bowel syndromea

76 (37.4)

16 (23.2)

26 (38.2)

34 (51.5)

0.003

 Seasonal allergies

70 (34.5)

24 (34.8)

20 (29.4)

26 (39.4)

0.464

 Dyslipidemia

64 (31.5)

22 (31.9)

19 (27.9)

23 (34.8)

0.689

 Gastroesophageal reflux disease

60 (29.6)

22 (31.9)

17 (25.0)

21 (31.8)

0.604

 Sleep apnea

53 (26.1)

15 (21.7)

18 (26.5)

20 (30.3)

0.501

Prescription medication ever taken, n (%)c

 Biologic

176 (86.7)

–

–

–

–

 Nonbiologic DMARD

174 (85.7)

–

–

–

–

 Antidepressant

109 (53.7)

–

–

–

–

 Steroid medication

162 (79.8)

–

–

–

–

 NSAID

167 (82.3)

–

–

–

–

 Opioid pain medication

96 (47.3)

–

–

–

–

 Other pain medication

132 (65.0)

–

–

–

–

 Sleep medication

67 (33.0)

–

–

–

–

 Other

58 (28.6)

–

–

–

–

 None

3 (1.5)

–

–

–

–

  1. a P < 0.05 comparing respondents with time to PsA diagnosis of < 6 months, 6 months to 4 years, and ≥ 5 years
  2. b Extent of psoriasis may be higher due to effects of treatment on reduction of symptom presentation of psoriasis
  3. c Respondents could have selected > 1 option
  4. DMARD disease-modifying antirheumatic drug, NSAID nonsteroidal anti-inflammatory drug, PsA psoriatic arthritis, RAPID3 Routine Assessment of Patient Index Data 3