Skip to main content

Table 1 Characteristics of patients and controls

From: Use of antidepressants and benzodiazepine-related hypnotics before and after initiation of TNF-α inhibitors or non-biological systemic treatment in patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis

N6256 13,241 
Women, %61.6 60.5 
 Age mean (SD)52.0(14.5)56.1(16.3)
 Baseline rate, %11.8 10.9 
 Controls, %6.6 7.6 
 Difference (95% c.i.)5.2(4.35–5.99)3.3(2.77–3.87)
Benzodiazepine-related hypnotics
 Baseline rate, %10.7 10.4 
 Controls, %6.6 7.6 
 Difference (95% c.i.)4.13.34–4.922.82.25–3.33
Number of drugs (substances, 3 months before index)
  mean (SD)6.9(4.2)6.5(3.8)
  mean (SD)2.0(3.0)2.3(3.1)
Number of outpatient visits (past 12 months)
  mean (SD)5.6(4.1)3.0(3.7)
  mean (SD)0.8(2.3)0.8(2.4)
Proportion, at least one hospitalization (past 12 months)
 Patients, %20 21 
 Controls, %9 10 
  1. TNF TNF-α inhibitors, NBS Non-biologic systemic