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Fig. 2 | BMC Rheumatology

Fig. 2

From: Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study

Fig. 2

AlamarBlue® metabolic activity assessment of the bovine articular cartilage explants over a three-week culture period. a Metabolic activity, reported as a fluorescence (590–540 nm) readout, at day 0, 7, 14 and 21 in conditioned media from untreated BEX explants, or BEX explants treated with OSM [10 ng/mL] + TNFα [20 ng/mL], or IL-17A [100 ng/ml or 25 ng/ml]. b Area under the curve (AUC) was calculated from each explant’s fluorescence readout over time. Data is presented as means; bars represent SD and ns indicates no statistically significant difference between either one of the treatment groups compared to the untreated group (Kruskall-Wallis test with Dunn’s post-hoc test for multiple comparisons where p < 0.05 was considered significant)

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