Table 1 Characteristics of subjects

Age (years)

71.4 ± 14.2

69.7 ± 13.2

69.3 ± 12.0

Gender (male:female)

17: 13

17: 13

21: 19

Birmingham vasculitis activity score

20.7 ± 5.2^{*, **}

0 ± 0

 Fever

21 (70%)^*

0 (0%)

 Weight loss

10 (33%)^*

0 (0%)

 Arthralgia

22 (73%)^*

0 (0%)

 Episcleritis or uvitis

2 (7%)

0 (0%)

 Sinusitis

1 (3%)

0 (0%)

 Hearing loss

3 (10%)

0 (0%)

 Alveolar hemorrhage

5 (17%)

0 (0%)

 Interstitial lung disease

15 (50%)

13 (43%)

 Arrhythmia

3 (10%)

0 (0%)

 Pericarditis

2 (7%)

0 (0%)

 Heart failure

9 (30%)^*

0 (0%)

 Rapidly progressive glomerulonephritis

25 (83%)^*

0 (0%)

 Peripheral nerve damage

1 (3%)

0 (0%)

 ANCA titer (U/mL)

255.7 ± 178.8^{*, **}

14.2 ± 30.4

 White blood cell (/mm³)

9483 ± 3380^{*, **}

8923 ± 3234^**

5763 ± 1482

 Hemoglobin conc. (g/dL)

9.1 ± 2.0^{*, **}

11.7 ± 1.8

12.1 ± 2.0

 Platelet count (10⁴/mm³)

27.2 ± 12.0^{*, **}

21.2 ± 5.4

20.2 ± 6.0

 Serum albumin (g/dL)

3.05 ± 0.60^{*, **}

3.74 ± 0.37^**

4.10 ± 0.34

 Serum creatinine (mg/dL)

4.55 ± 3.33^{*, **}

3.26 ± 3.96

1.76 ± 1.48

 Serum C-reactive protein (mg/dL)

7.92 ± 6.87^{*, **}

0.18 ± 0.16

0.09 ± 0.12

 Serum 20S-proteasome (mg/dL)

3414.6 ± 2738.9^{*, **}

366.4 ± 128.4

234.9 ± 90.1

Doses of prednisolone (mg daily)

0 ± 0^*

5.00 ± 1.97