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Table 1 Summary of laboratory investigations at baseline and follow-ups

From: Mixed Cryoglobulinemia Syndrome (MCS) due to untreated hepatitis B with uncommon presentation: case report and literature review

Lab value

Baseline

1st admission

2nd admission

3 months after starting treatment

Reference value

BUN

12

8

10

9

5–25 mg/dl

Creatinine

0.72

0.87

0.87

0.90

0.61–1.24 mg/dl

GFR

> 60

> 60

> 60

87

> 60

AST

19

28

32

18

10–42 U/L

ALT

12

18

27

12

10–60 U/L

ALP

77

82

69

103

38–126 U/L

INR

1.00

0.92

0.96

–

0.88–1.15

PTT

32

32

31

–

26–39 s

WBC

10.3

6.6

6

6.3

4.5–11.0 K/uL

Hemoglobin

13.0

14.6

13.4

15.4

13.2–17.5 g/dl

Platelets

163

203

187

213

140–450 K/uL

ESR

19

13

44

20

0–15 mm/h

CRP

–

21.9

–

2

0–10 mg/L

C3

–

54.8

–

87

85–170 mg/dl

C4

–

< 2

–

7

16–40 mg/dl

RF

–

2460.0

–

–

< 20 U/mL

c-ANCA

–

< 1:20

–

–

<  1:20

p-ANCA

–

0

–

–

0–19 U/mL

Cryoglobulin screen

–

Positive

–

Positive

Non-detected

Cryoprecipitan IFE

–

Type II

–

Type II

–

IGA cryprecipitate

–

15

–

–

0 mg/dl

IGG cryprecipitate

–

97

–

–

0 mg/dl

IGM cryprecipitate

–

109

–

–

0 mg/dl

QuantiFERON TB

–

Negative

–

–

–

Hep B surface Ag

–

Positive

–

Positive

–

Hep B core IgM Ab

–

Negative

–

Negative

–

Hep B surface Ab

–

Negative

–

Negative

–

Hep B NAAT

 

530 IU/mL

–

Undetected

–

Hep C Ab

–

Negative

–

–

–

Hep A Ab IgM

–

Negative

–

–

–

HIV 1 & 2 Ag/AB

–

Negative

–

–

–