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Table 1 Summary of laboratory investigations at baseline and follow-ups

From: Mixed Cryoglobulinemia Syndrome (MCS) due to untreated hepatitis B with uncommon presentation: case report and literature review

Lab value Baseline 1st admission 2nd admission 3 months after starting treatment Reference value
BUN 12 8 10 9 5–25 mg/dl
Creatinine 0.72 0.87 0.87 0.90 0.61–1.24 mg/dl
GFR > 60 > 60 > 60 87 > 60
AST 19 28 32 18 10–42 U/L
ALT 12 18 27 12 10–60 U/L
ALP 77 82 69 103 38–126 U/L
INR 1.00 0.92 0.96 0.88–1.15
PTT 32 32 31 26–39 s
WBC 10.3 6.6 6 6.3 4.5–11.0 K/uL
Hemoglobin 13.0 14.6 13.4 15.4 13.2–17.5 g/dl
Platelets 163 203 187 213 140–450 K/uL
ESR 19 13 44 20 0–15 mm/h
CRP 21.9 2 0–10 mg/L
C3 54.8 87 85–170 mg/dl
C4 < 2 7 16–40 mg/dl
RF 2460.0 < 20 U/mL
c-ANCA < 1:20 <  1:20
p-ANCA 0 0–19 U/mL
Cryoglobulin screen Positive Positive Non-detected
Cryoprecipitan IFE Type II Type II
IGA cryprecipitate 15 0 mg/dl
IGG cryprecipitate 97 0 mg/dl
IGM cryprecipitate 109 0 mg/dl
QuantiFERON TB Negative
Hep B surface Ag Positive Positive
Hep B core IgM Ab Negative Negative
Hep B surface Ab Negative Negative
Hep B NAAT   530 IU/mL Undetected
Hep C Ab Negative
Hep A Ab IgM Negative
HIV 1 & 2 Ag/AB Negative