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Table 1 Baseline characteristics of patients with RA with persistent moderate disease activity

From: Factors associated with disability in patients with rheumatoid arthritis with persistent moderate disease activity: a retrospective cohort study

Baseline variable Biologic naïve
(N = 207)
Biologic experienced
(N = 188)
Age (years) 58.5 ± 15.6 55.4 ± 14.1
Female 167 (81) 153 (81)
Ethnicity White 140 (70) 112 (74)
Black 33 (17) 25 (17)
Asian 12 (6) 6 (4)
Mixed 4 (2) 3 (2)
Other 9 (5) 5 (3)
Duration of RA (years) 7.0 ± 9.0 21.1 ± 12.0
RF positive 105 (64) 131 (80)
Anti-CCP positive 69 (54) 65 (59)
Corticosteroids 22 (11) 38 (20)
Treatment: Biologic naïve Monotherapy 99 (52)
Combination 89 (47)
None 3 (2)
Treatment: Biologic experienced DMARD 51 (30)
Biologic 25 (15)
DMARD – biologic 94 (55)
DAS28-ESR 4.0 ± 0.5 4.1 ± 0.5
28-TJC 4.3 ± 4.3 4.9 ± 4.2
28-SJC 2.1 ± 2.8 2.7 ± 2.6
PtGA 50.0 ± 21.8 51.0 ± 21.4
ESR 21.8 ± 16.3 20.0 ± 16.1
HAQ-DI 1.2 ± 0.8 1.5 ± 0.7
EQ-5D-3L index 0.5 ± 0.3 0.5 ± 0.3
EQ-5D-3L pain None 12 (7) 8 (4)
Moderate 135 (79) 153 (82)
Severe 23 (14) 26 (14)
EQ-5D-3L anxiety/depression None 92 (55) 91 (49)
Moderate 64 (38) 87 (47)
Severe 12 (7) 8 (4)
  1. Results are presented as n (%) or mean ± standard deviation. The following data are missing in the biologic-naïve population: ethnicity in 9 patients; disease duration in 7 patients; RF in 43 patients; anti-CCP in 80 patients; DMARD treatment in 16 patients; TJC/SJC/PtGA in 1 patient; ESR in 6 patients; EQ-5D-3L index scores in 35 patients. The following data are missing in the biologic-experienced population: sex in 2 patients; ethnicity in 37 patients; RF in 25 patients; anti-CCP in 78 patients; DMARD treatment in 18 patients; PtGA in 1 patient; ESR in 12 patients; EQ-5D-3L index scores in 1 patient
  2. Abbreviations: CCP cyclic citrullinated peptide antibody, DAS28-ESR Disease Activity Score for 28-joint count based on erythrocyte sedimentation rate, DMARD disease-modifying anti-rheumatic drug, EQ-5D-3L 3-level EuroQol 5-dimensions questionnaire, ESR erythrocyte sedimentation rate, HAQ-DI Health Assessment Questionnaire-Disability Index, PtGA patient global assessment, RA rheumatoid arthritis, RF rheumatoid factor, SJC swollen joint count, TJC tender joint count