Baseline variable | 12-month HAQ-DI score | 12-month change in HAQ-DI score | 12-month EQ-5D-3L score | 12-month change in EQ-5D-3L score | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |||||||||
β | P | β | P | β | P | β | P | β | P | β | P | β | P | β | P | |
Age | 0.01 | 0.003 | 0.00 | 0.554 | 0.00 | 0.698 | – | – | 0.00 | 0.510 | – | – | 0.00 | 0.510 | – | – |
Male sex | −0.06 | 0.679 | – | – | 0.07 | 0.468 | – | – | −0.30 | 0.119 | – | – | 0.01 | 0.886 | – | – |
White | Ref | – | – | – | Ref | – | – | – | Ref | – | Ref | – | Ref | – | Ref | – |
Black | −0.23 | 0.173 | – | – | −0.08 | 0.527 | – | – | 0.12 | 0.574 | – | – | 0.03 | 0.620 | – | – |
Asian | −0.39 | 0.218 | – | – | −0.10 | 0.658 | – | – | 0.17 | 0.672 | – | – | −0.08 | 0.542 | – | – |
Mixed | −0.43 | 0.328 | – | – | −0.07 | 0.813 | – | – | 0.66 | 0.341 | – | – | 0.05 | 0.815 | – | – |
Other | −0.05 | 0.888 | – | – | −0.26 | 0.291 | – | – | 0.51 | 0.255 | – | – | 0.23 | 0.106 | – | – |
Disease duration | 0.00 | 0.667 | – | – | 0.00 | 0.845 | – | – | 0.01 | 0.395 | – | – | 0.00 | 0.862 | – | – |
RF positive | −0.14 | 0.342 | – | – | −0.12 | 0.249 | – | – | 0.12 | 0.535 | – | – | 0.02 | 0.730 | – | – |
Corticosteroids | 0.31 | 0.026 | 0.09 | 0.369 | 0.00 | 0.968 | – | – | −0.12 | 0.490 | – | – | 0.03 | 0.572 | – | – |
DAS28-ESR | 0.00 | 0.986 | – | – | −0.14 | 0.057 | 0.01 | 0.891 | 0.00 | 0.990 | – | – | 0.09 | 0.053 | 0.05 | 0.269 |
Swollen joint count | −0.04 | 0.049 | −0.01 | 0.391 | 0.00 | 0.991 | – | – | 0.04 | 0.138 | – | – | 0.01 | 0.510 | – | – |
Tender joint count | −0.02 | 0.139 | – | – | −0.02 | 0.001 | −0.03 | 0.006 | 0.01 | 0.572 | – | – | 0.01 | 0.161 | – | – |
PtGA | 0.01 | 0.014 | 0.00 | 0.401 | 0.00 | 0.060 | 0.00 | 0.421 | −0.01 | 0.028 | 0.00 | 0.850 | 0.00 | 0.047 | 0.00 | 0.293 |
ESR | 0.00 | 0.628 | – | – | 0.00 | 0.754 | – | – | 0.00 | 0.222 | – | – | 0.00 | 0.774 | – | – |
DMARD | Ref | – | – | – | Ref | – | – | – | Ref | – | Ref | – | Ref | – | Ref | – |
Biologic | 0.11 | 0.561 | – | – | 0.08 | 0.530 | – | – | 0.08 | 0.899 | – | – | −0.04 | 0.604 | – | – |
DMARD biologic | 0.02 | 0.902 | – | – | −0.01 | 0.882 | – | – | −0.02 | 0.899 | – | – | −0.04 | 0.472 | – | – |
HAQ-DI | 0.79 | < 0.001 | 0.76 | < 0.001 | −0.21 | < 0.001 | −0.21 | < 0.001 | − 0.49 | < 0.001 | −0.29 | 0.004 | 0.03 | 0.283 | – | – |
EQ-5D-3L index | −1.08 | < 0.001 | −0.02 | 0.949 | 0.28 | 0.053 | −0.10 | 0.546 | 1.61 | < 0.001 | 1.18 | 0.007 | −0.50 | < 0.001 | −0.40 | 0.003 |
EQ-5D-3L pain | 0.33 | 0.012 | 0.01 | 0.935 | −0.11 | 0.211 | – | – | −0.53 | 0.002 | 0.23 | 0.325 | 0.29 | < 0.001 | 0.13 | 0.090 |
EQ-5D-3L anxiety/depression | 0.23 | 0.019 | 0.05 | 0.544 | −0.01 | 0.875 | – | – | −0.54 | < 0.001 | −0.25 | 0.058 | 0.09 | 0.026 | −0.02 | 0.674 |