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Table 2 The comorbidities and status of patients with RA at ICU admission

From: Prognostic factors for the short-term mortality of patients with rheumatoid arthritis admitted to intensive care units

 

All patients (n = 67)

30-day mortality

Survivors (n = 52)

Nonsurvivors (n = 15)

P value

Updated CCI

 Congestive heart failure (0/2)

0.3 ± 0.7

(0, 0–2)

0.2 ± 0.6

(0, 0–2)

0.5 ± 0.9

(0, 0–2)

0.0904

 Dementia (0/2)

0.09 ± 0.4

(0, 0–2)

0.04 ± 0.3

(0, 0–2)

0.3 ± 0.7

(0, 0–2)

0.0617

 Chronic pulmonary disease (0/1)

0.3 ± 0.5

(0, 0–2)

0.3 ± 0.5

(0, 0–2)

0.4 ± 0.5

(0, 0–2)

0.5056

 Rheumatologic disease (0/1)

1

1

1

ns

 Liver disease (0/2/4)

0.6 ± 1.3

(0, 0–4)

0.2 ± 0.8

(0, 0–4)

1.7 ± 2.0

(0, 0–4)

0.0004

 Diabetes with chronic complications (0/1)

0.2 ± 0.6

(0, 0–1)

0.2 ± 0.6

(0, 0–1)

0.1 ± 0.5

(0, 0–1)

0.5896

 Hemiplegia/paraplegia (0/2)

0.2 ± 0.6

(0, 0–2)

0.2 ± 0.6

(0, 0–2)

0

(0, 0)

0.1712

 Renal disease (0/1)

0.3 ± 0.5

(0, 0–1)

0.2 ± 0.4

(0, 0–1)

0.7 ± 0.5

(1, 0–1)

0.0009

 Malignancy (0/2/6)

0.3 ± 0.9

(0, 0–6)

0.3 ± 0.7

(0, 0–2)

0.4 ± 1.5

(0, 0–6)

0.5383

 AIDS/HIV (0/4)

0

0

0

ns

 Total CCI (0–24)

3.3 ± 2.0

(3, 1–12)

2.7 ± 1.4

(3, 1–6)

5.1 ± 2.5

(4, 2–12)

0.0001

 APACHE II (0–71)

16.2 ± 7.1

(15, 2–35)

14.6 ± 5.6

(14, 2–25)

21.7 ± 9.2

(24, 2–35)

0.0029

 ICU stay (days)

7.3 ± 7.7

(4, 2–39)

6.6 ± 7.5

(4, 2–39)

9.4 ± 8.4

(5, 2–30)

0.1153

 Hospitalization (days)

42.1 ± 35.1

(30, 3–176)

46.2 ± 36.5

(34, 5–176)

27.8 ± 25.6

(24, 3–104)

0.0302

 DIC score

3.6 ± 2.6

(3, 1–11)

2.8 ± 1.9

(2, 1–11)

6.4 ± 2.9

(7, 2–11)

< 0.0001

Reason for ICU admission

   

0.3239

 Cardiovascular disease

16 (24%)

15 (29%)

1 (7%)

 

 Infection

27 (40%)

17 (33%)

10 (67%)

 

 Liver failure

2 (3%)

1 (2%)

1 (7%)

 

 Respiratory disorder

9 (13%)

7 (13%)

2 (13%)

 

 Gastrointestinal tract disorder

1 (1%)

1 (2%)

0 (0%)

 

 Neurological disorder

4 (6%)

4 (8%)

0 (0%)

 

 Renal failure

3 (4%)

3 (6%)

0 (0%)

 

 Others

5 (7%)

4 (8%)

1 (7%)

 

ICU treatment

 Mechanical ventilation

46 (69%)

34 (65%)

12 (80%)

0.2824

 Renal replacement therapy

17 (25%)

8 (15%)

9 (60%)

0.0005

 Plasma exchange therapy

3 (4%)

1 (2%)

2 (13%)

0.0598

 Vasopressor therapy

52 (78%)

40 (77%)

12 (80%)

0.8012

 Antibiotic therapy

39 (58%)

27 (52%)

12 (80%)

0.0521

  1. Data represent means ± SD (median, range)
  2. AIDS acquired immunodeficiency syndrome, APACHE II acute physiology and chronic health evaluation II, CCI Charlson’s comorbidity index, DIC disseminated intravascular coagulation, HIV human immunodeficiency virus, ICU intensive care unit, ns not significant
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BMC Rheumatology

ISSN: 2520-1026

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