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Table 2 The comorbidities and status of patients with RA at ICU admission

From: Prognostic factors for the short-term mortality of patients with rheumatoid arthritis admitted to intensive care units

  All patients (n = 67) 30-day mortality
Survivors (n = 52) Nonsurvivors (n = 15) P value
Updated CCI
 Congestive heart failure (0/2) 0.3 ± 0.7
(0, 0–2)
0.2 ± 0.6
(0, 0–2)
0.5 ± 0.9
(0, 0–2)
0.0904
 Dementia (0/2) 0.09 ± 0.4
(0, 0–2)
0.04 ± 0.3
(0, 0–2)
0.3 ± 0.7
(0, 0–2)
0.0617
 Chronic pulmonary disease (0/1) 0.3 ± 0.5
(0, 0–2)
0.3 ± 0.5
(0, 0–2)
0.4 ± 0.5
(0, 0–2)
0.5056
 Rheumatologic disease (0/1) 1 1 1 ns
 Liver disease (0/2/4) 0.6 ± 1.3
(0, 0–4)
0.2 ± 0.8
(0, 0–4)
1.7 ± 2.0
(0, 0–4)
0.0004
 Diabetes with chronic complications (0/1) 0.2 ± 0.6
(0, 0–1)
0.2 ± 0.6
(0, 0–1)
0.1 ± 0.5
(0, 0–1)
0.5896
 Hemiplegia/paraplegia (0/2) 0.2 ± 0.6
(0, 0–2)
0.2 ± 0.6
(0, 0–2)
0
(0, 0)
0.1712
 Renal disease (0/1) 0.3 ± 0.5
(0, 0–1)
0.2 ± 0.4
(0, 0–1)
0.7 ± 0.5
(1, 0–1)
0.0009
 Malignancy (0/2/6) 0.3 ± 0.9
(0, 0–6)
0.3 ± 0.7
(0, 0–2)
0.4 ± 1.5
(0, 0–6)
0.5383
 AIDS/HIV (0/4) 0 0 0 ns
 Total CCI (0–24) 3.3 ± 2.0
(3, 1–12)
2.7 ± 1.4
(3, 1–6)
5.1 ± 2.5
(4, 2–12)
0.0001
 APACHE II (0–71) 16.2 ± 7.1
(15, 2–35)
14.6 ± 5.6
(14, 2–25)
21.7 ± 9.2
(24, 2–35)
0.0029
 ICU stay (days) 7.3 ± 7.7
(4, 2–39)
6.6 ± 7.5
(4, 2–39)
9.4 ± 8.4
(5, 2–30)
0.1153
 Hospitalization (days) 42.1 ± 35.1
(30, 3–176)
46.2 ± 36.5
(34, 5–176)
27.8 ± 25.6
(24, 3–104)
0.0302
 DIC score 3.6 ± 2.6
(3, 1–11)
2.8 ± 1.9
(2, 1–11)
6.4 ± 2.9
(7, 2–11)
< 0.0001
Reason for ICU admission     0.3239
 Cardiovascular disease 16 (24%) 15 (29%) 1 (7%)  
 Infection 27 (40%) 17 (33%) 10 (67%)  
 Liver failure 2 (3%) 1 (2%) 1 (7%)  
 Respiratory disorder 9 (13%) 7 (13%) 2 (13%)  
 Gastrointestinal tract disorder 1 (1%) 1 (2%) 0 (0%)  
 Neurological disorder 4 (6%) 4 (8%) 0 (0%)  
 Renal failure 3 (4%) 3 (6%) 0 (0%)  
 Others 5 (7%) 4 (8%) 1 (7%)  
ICU treatment
 Mechanical ventilation 46 (69%) 34 (65%) 12 (80%) 0.2824
 Renal replacement therapy 17 (25%) 8 (15%) 9 (60%) 0.0005
 Plasma exchange therapy 3 (4%) 1 (2%) 2 (13%) 0.0598
 Vasopressor therapy 52 (78%) 40 (77%) 12 (80%) 0.8012
 Antibiotic therapy 39 (58%) 27 (52%) 12 (80%) 0.0521
  1. Data represent means ± SD (median, range)
  2. AIDS acquired immunodeficiency syndrome, APACHE II acute physiology and chronic health evaluation II, CCI Charlson’s comorbidity index, DIC disseminated intravascular coagulation, HIV human immunodeficiency virus, ICU intensive care unit, ns not significant