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Table 1 Clinical and laboratory findings in our study population. Values are presented as mean ± SD or frequency (percent) when appropriate

From: Retinopathy in newly-diagnosed systemic lupus erythematosus: should we screen for ocular involvement?

Variable All patients (n = 114) Patients with retinopathy (n = 18) Patients without retinopathy (n = 96) P value
Age (years) 31.4 ± 9.5 28.1 ± 10.3 32 ± 9.2 0.08
Female gender 99 (87) 16 (89) 83 (86) 0.77
Clinical findings
 Fever 18 (16) 4 (22) 14 (15) 0.41
 Headache 7 (6) 2 (11) 5 (5) 0.33
 CVA 2 (2) 0 (0) 2 (2) 0.7
 Psychosis/delirium 1 (1) 1 (6) 0 (0) 0.15
 Seizure 21 (18) 4 (22) 17 (18) 0.65
 Oral ulcers 12 (11) 4 (22) 8 (8) 0.07
 Rash 66 (58) 11 (61) 55 (57) 0.76
 Vasculitis 15 (13) 2 (11) 13 (13) 0.78
 Arthritis 88 (77) 14 (78) 74 (77) 0.94
 Myositis 3 (3) 0 (0) 3 (3) 0.44
Laboratory findings
 WBC count 6505 ± 3053 5559 ± 2971 6683 ± 3051 0.15
 Hemoglobin (mg/dl) 10.8 ± 1.8 10 ± 2.1 11 ± 1.8 0.01
 Platelet count 2.14*105 ± 1.16*105 2.46*105 ± 1.38*105 2.09*105 ± 1.12*105 0.24
 ESR (mm/hr) 44.5 ± 27.5 53 ± 24 43 ± 28 0.14
 CRP (mg/L) 13.6 ± 31.5 33 ± 70 10 ± 15 0.65
 Serum creatinine (mg/dl) 0.80 ± 0.27 0.91 ± 0.31 0.79 ± 0.27 0.475
 Urinalysis
  Proteinuria (mg/g) 773 ± 308 905 ± 350 749 ± 295 0.18
  Casts 8 (7) 4 (22) 4 (14) 0.006
 AST 42.1 ± 60.6 64 ± 66 38 ± 59 0.056
 ALT 42.7 ± 75.8 52 ± 71 41 ± 77 0.053
 Anti-Cardiolipin Ab 14.8 ± 25.0 14 ± 20 15 ± 26 0.29
 ANA 4.6 ± 0.95 5.7 ± 1.1 4.5 ± 0.8 0.01
 Anti-dsDNA 77.0 ± 22.5 109 ± 22 71 ± 17 0.04
 Serum C3 80.2 ± 18.5 55 ± 15 85 ± 15 0.001
 Serum C4 77.6 ± 33.2 12 ± 10 90 ± 18 0.03
SLE DAI 12.7 ± 7.4 22 ± 7.9 11 ± 6 < 0.001
  1. Significant comparisons are indicated in bold
  2. CVA cerebrovascular accident, WBC white blood cells, ESR erythrocyte sedimentation rate, CRP c-reactive protein, AST aspartate transaminase, ALT alanine transaminase, ANA anti-nuclear antibody, SLE DAI systemic lupus erythematous disease activity index