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Table 1 Clinical and laboratory findings in our study population. Values are presented as mean ± SD or frequency (percent) when appropriate

From: Retinopathy in newly-diagnosed systemic lupus erythematosus: should we screen for ocular involvement?

Variable

All patients (n = 114)

Patients with retinopathy (n = 18)

Patients without retinopathy (n = 96)

P value

Age (years)

31.4 ± 9.5

28.1 ± 10.3

32 ± 9.2

0.08

Female gender

99 (87)

16 (89)

83 (86)

0.77

Clinical findings

 Fever

18 (16)

4 (22)

14 (15)

0.41

 Headache

7 (6)

2 (11)

5 (5)

0.33

 CVA

2 (2)

0 (0)

2 (2)

0.7

 Psychosis/delirium

1 (1)

1 (6)

0 (0)

0.15

 Seizure

21 (18)

4 (22)

17 (18)

0.65

 Oral ulcers

12 (11)

4 (22)

8 (8)

0.07

 Rash

66 (58)

11 (61)

55 (57)

0.76

 Vasculitis

15 (13)

2 (11)

13 (13)

0.78

 Arthritis

88 (77)

14 (78)

74 (77)

0.94

 Myositis

3 (3)

0 (0)

3 (3)

0.44

Laboratory findings

 WBC count

6505 ± 3053

5559 ± 2971

6683 ± 3051

0.15

 Hemoglobin (mg/dl)

10.8 ± 1.8

10 ± 2.1

11 ± 1.8

0.01

 Platelet count

2.14*105 ± 1.16*105

2.46*105 ± 1.38*105

2.09*105 ± 1.12*105

0.24

 ESR (mm/hr)

44.5 ± 27.5

53 ± 24

43 ± 28

0.14

 CRP (mg/L)

13.6 ± 31.5

33 ± 70

10 ± 15

0.65

 Serum creatinine (mg/dl)

0.80 ± 0.27

0.91 ± 0.31

0.79 ± 0.27

0.475

 Urinalysis

  Proteinuria (mg/g)

773 ± 308

905 ± 350

749 ± 295

0.18

  Casts

8 (7)

4 (22)

4 (14)

0.006

 AST

42.1 ± 60.6

64 ± 66

38 ± 59

0.056

 ALT

42.7 ± 75.8

52 ± 71

41 ± 77

0.053

 Anti-Cardiolipin Ab

14.8 ± 25.0

14 ± 20

15 ± 26

0.29

 ANA

4.6 ± 0.95

5.7 ± 1.1

4.5 ± 0.8

0.01

 Anti-dsDNA

77.0 ± 22.5

109 ± 22

71 ± 17

0.04

 Serum C3

80.2 ± 18.5

55 ± 15

85 ± 15

0.001

 Serum C4

77.6 ± 33.2

12 ± 10

90 ± 18

0.03

SLE DAI

12.7 ± 7.4

22 ± 7.9

11 ± 6

< 0.001

  1. Significant comparisons are indicated in bold
  2. CVA cerebrovascular accident, WBC white blood cells, ESR erythrocyte sedimentation rate, CRP c-reactive protein, AST aspartate transaminase, ALT alanine transaminase, ANA anti-nuclear antibody, SLE DAI systemic lupus erythematous disease activity index