Skip to main content

Table 3 Cox proportional hazards models for the entire group, males, and females (adjusted for the following covariates: age, ethnicity and original cohort, in addition to gender for the entire group analysis)

From: Longitudinal development of incident gout from low-normal baseline serum urate concentrations: individual participant data analysis

  Adjusted models
Serum urate Beta SE P Hazard ratio 95% Lower CI 95% Upper CI
Referant < 4.0 mg/dL
All 4.0–4.49 mg/dL 0.671 0.343 0.050 1.96 1.00 3.83
4.5–4.99 mg/dL 0.357 0.347 0.304 1.43 0.72 2.82
5.0–5.49 mg/dL 0.502 0.335 0.134 1.65 0.86 3.19
5.5–5.99 mg/dL 0.957 0.317 0.003 2.60 1.40 4.85
6.0–6.49 mg/dL 1.308 0.308 0.000 3.70 2.02 6.77
6.5–6.99 mg/dL 1.657 0.305 0.000 5.24 2.88 9.53
≥7.00 mg/dL 2.924 0.279 0.000 18.62 10.78 32.15
Male 4.0–4.49 mg/dL 0.068 0.646 0.916 1.07 0.30 3.80
4.5–4.99 mg/dL −0.381 0.627 0.543 0.68 0.20 2.33
5.0–5.49 mg/dL −0.767 0.628 0.222 0.46 0.14 1.59
5.5–5.99 mg/dL 0.119 0.551 0.829 1.13 0.38 3.32
6.0–6.49 mg/dL 0.593 0.532 0.264 1.81 0.64 5.13
6.5–6.99 mg/dL 0.922 0.528 0.081 2.51 0.89 7.07
≥7.00 mg/dL 2.105 0.508 0.000 8.21 3.04 22.20
Female 4.0–4.49 mg/dL 0.649 0.406 0.110 1.91 0.86 4.25
4.5–4.99 mg/dL 0.369 0.422 0.381 1.45 0.63 3.31
5.0–5.49 mg/dL 0.819 0.399 0.040 2.27 1.04 4.95
5.5–5.99 mg/dL 0.981 0.412 0.017 2.67 1.19 5.98
6.0–6.49 mg/dL 1.052 0.438 0.016 2.86 1.21 6.76
6.5–6.99 mg/dL 1.422 0.439 0.001 4.14 1.75 9.80
≥7.00 mg/dL 2.958 0.345 0.000 19.27 9.80 37.87
  1. Abbreviations: SE Standard error, CI Confidence Interval