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Table 2 Clinical Features

From: The frequency of Raynaud’s phenomenon, very early diagnosis of systemic sclerosis, and systemic sclerosis in a large Veteran Health Administration database

  No RP, VEDOSS, or SSc (n = 606,692) Raynauds Phenomenon
(n = 857)
VEDOSS
(n = 49)
Systemic Sclerosis
(n = 71)
Vasodilator use 92,530 (15%) 410 (48%) 21 (47%) 45 (63%)
Pain 228,045 (38%) 493 (58%) 37 (82%) 46 (65%)
Fecal incontinence 829 (0.1%) < 1% < 5% < 5%
Esophageal Dyskinesia 564 (0.1%) < 1% 0 < 10%a
Interstitial Lung Disease 11 (0%) 0 0 < 5%a
Pulmonary Arterial Hypertension 542 (0.1%) < 1% 0 15 (21%)a
Cancer 8736 (1%) 27 (3%) 0 < 5%
High Blood Pressure 120,368 (20%) 222 (26%)a 13 (29%) 33 (47%)a
Diabetes 29,780 (5%) 34 (4%) < 5% < 10%
Anxiety 145,477 (24%) 269 (31%) 11 (24%) 21 (30%)
Heart Disease 19,297 (3%) 50 (6%) < 15% < 15%
Liver Disease 9740 (2%) 14 (2%) 0 < 10%
Kidney Disease 4545 (1%) 18 (2%) 0 < 5%
Suicidal ideation/attempt 32,050 (5%) 59 (7%) < 10% < 10%
Obesity 122,838 (20%) 134 (16%) < 25% 12 (17%)
Seizures 8821 (2%) 21 (2%) < 5% < 5%
Depression 219,302 (36%) 384 (45%)a 22 (49%)a 39 (55%)a
PTSD 257,801 (42%) 394 (46%) 22 (49%) 26 (37%)
  1. adenotes statistical significance across the categories from no conditions, RP, VEDOSS and SSc