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Table 3 Hazards ratios and 95% confidence intervals of Alzheimer’s disease in IMID, the health and retirement study 2009–2014

From: No increased risk of Alzheimer’s disease among people with immune-mediated inflammatory diseases: findings from a longitudinal cohort study of U.S. older adults

Predictors

Unadjusted Hazards Ratio

p

Adjusted Hazards Ratios

p

IMID

1.09 (.66–1.81)

0.74

1.27 (.76–2.12)

0.35

Age (10 year increment)

  

3.56 (2.69–4.72)

* < .001

Age Squared (10 year increment)

  

.97 (.95–.99)

*.006

Gender (reference male) Female

  

.96 (.74–1.24)

0.73

Race (reference White) Non-White

  

1.4 (.92–2.13)

0.11

Education (reference two-year college or more)

 High School or Equivalent

  

1.24 (0.88–1.72)

0.22

 Less than High School

  

1.70 (1.15–2.50)

*.007

APOE e4 (Reference no copies)

 One or Two copies

  

2.61 (2.02–3.37)

* < .001

  1. IMID Immune-Mediated Inflammatory Disease
  2. APOE e4 Apolipoprotein e4
  3. Hazards Ratios Calculated using Cox Proportional Hazards Models
  4. * Denotes statistically significant p-value at .05 alpha