From: Macrophage activation syndrome in MDA5 antibody-positive dermatomyositis and COVID-19 infection
HLH-2004 criteria | Our patient |
---|---|
Fever ≥  38.5 °C | Fever with temperature at 40 °C |
Peripheral blood cytopenia, with at least two of the following: hemoglobin < 9 g/dL (for infants < 4 weeks, hemoglobin < 10 g/dL); platelets < 100,000/microL; absolute neutrophil count < 1000/microL | Hemoglobin 7.8 gm/dl and platelet count 83 k/µL |
Hypertriglyceridemia (fasting triglycerides > 265 mg/dL) and hypofibrinogenemia (fibrinogen < 150 mg/dL) | Triglyceride level 1100 mg/dl |
Ferritin > 500 ng/mL | Ferritin > 16,500 ng/mL |