Table 2 Overall (aggregate) associations between time-varying indices of disease activity and fatigue severity over time

0.651 (0.508–0.795)

0.274 (0.214–0.334)

8.934

 < 0.0001

0.041 (0.029–0.052)

0.150 (0.108–0.193)

6.922

 < 0.0001

0.037 (0.027–0.046)

0.197 (0.146–0.247)

7.648

 < 0.0001

0.192 (0.132–0.251)

0.121 (0.083–0.159)

6.315

 < 0.0001

0.200 (0.158–0.243)

0.180 (0.141–0.218)

9.197

 < 0.0001

0.041 (0.035–0.046)

0.352 (0.304–0.400)

14.394

 < 0.0001