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Table 1 Demographic, clinical, and treatment compliance characteristics of patients with inactive and active SLE

From: Impact of demographic, clinical, and treatment compliance characteristics on quality of life of Venezuelan patients with systemic lupus erythematosus

 

All (N = 100)

Inactivea (N = 64)

Activeb (N = 36)

p value

Demographic characteristics

Age, mean (SD), years

43 (14)

42 (13)

45 (14)

0.175*

Sex, women/men (%)

93/7 (93/7)

61/3 (95.3/4.7)

32/4 (88.9/11.1)

0.424

Education, median [IQR], years

11 [5]

11 [5]

11 [9]

0.754§

Current academic status, studying/not studying (%)

12/88 (12/88)

8/56 (12.5/87.5)

4/32 (11.1/88.9)

1

Current employment status, employed/unemployed (%)

38/62 (38/62)

27/37 (42.2/57.8)

11/25 (30.6/69.4)

0.349

Clinical characteristics

Disease duration, median [IQR], years

8 [12]

7 [12]

10 [15]

0.835§

Disease activity (SLEDAI), median [IQR], points

2 [5]

0 [1]

6 [6]

< 0.001§

Accrued organ damage (SLICC-DI), median [IQR], points

0 [1]

0 [0]

1 [2]

< 0.001§

Treatment compliance

Indicated-treatment compliance, yes/no (%)

37/63 (37/63)

27/37 (42.2/57.8)

26/10 (72.2/27.8)

0.152†

Antimalarial indicated, yes/no (%)

90/10 (90/10)

59/5 (92.2/7.8)

31/5 (86.1/13.9)

0.532

Compliance, yes/no (%)

56/34 (62.2/37.8)

41/18 (69.5/30.5)

15/16 (48.4/51.6)

0.094||

Corticosteroid indicated, yes/no (%)

85/15 (85/15)

51/13 (79.7/20.3)

34/2 (94.4/5.6)

0.047||

Compliance, yes/no (%)

60/25 (70.6/29.4)

39/12 (76.5/23.5)

21/13 (61.8/38.2)

0.047

Immunosuppressant indicated, yes/no (%)

45/55 (45/55)

32/32 (50/50)

13/23 (36.1/63.9)

0.180||

Compliance, yes/no (%)

18/27 (40/60)

14/18 (43.7/56.3)

4/9 (30.8/69.2)

0.305||

Biological therapy indicated, yes/no (%)

5/95 (5/95)

3/61 (4.7/95.3)

2/34 (5.6/94.4)

1

Compliance, yes/no (%)

0/5 (0/100)

0/3 (0/100)

0/2 (0/100)

SLE flare-ups in the previous six months, yes/no (%)

33/67 (33/67)

17/47 (26.6/73.4)

16/20 (44.4/55.6)

0.068||

Merited hospitalisation, yes/no (%)

1/32 (3/97)

0/17 (0/100)

1/15 (6.2/93.8)

0.092

  1. SD standard deviation, IQR interquartile range, SLEDAI Systemic Lupus Erythematosus Disease Activity Index, SLICC-DI Systemic Lupus International Collaborating Clinics Damage Index, SLE systemic lupus erythematosus
  2. aInactive SLE was defined by a SLEDAI < 4
  3. bActive SLE was defined by a SLEDAI ≥ 4
  4. *Independent-samples Student’s t-test
  5. Yates’ chi-square test
  6. Fisher’s exact test
  7. §Median test
  8. ||Pearson’s chi-square test