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Table 4 Uric acid Genotype frequencies comparisons Asian, Native Hawaiian, and Pacific Islanders Subgroups

From: Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross-sectional study

Gene (SNP) Genotype EUR† % (n) Filipino % (n) Korean % (n) Japanese % (n) Native Hawaiian % (n) Marshallese % (n) Samoan % (n)
ABCG2
(rs2231142 G > T)
GG
GT
TT
82.3 (414)
16.5 (83)
1.2 (6)
28.4 (51)
51.4 (92)
20.1 (36)
56.5 (52)
31.5 (29)
12.0 (11)
56.7 (106)
35.3 (66)
8.0 (15)
75.5 (110)
23.1 (33)
1.4 (2)
68.0 (83)
28.7 (35)
3.3 (4)
48.9 (89)
40.1 (73)
11 (20)
SLC2A9
(rs734553 G > T)
GG
GT
TT
5.6 (28)
37.8 (190)
56.6 (285)

2.3 (4)
97.7 (172)

3.2 (3)
96.8 (90)

1.1 (2)
98.9 (183)
1.4 (2)
15.4 (22)
83.2 (119)


100 (121)

3.3 (6)
96.7 (176)
SLC17A1
(rs1183201 T > A)
AA
AT
TT
23.1 (116)
46.1 (232)
30.8 (155)
4.0 (7)
33.7 (59)
62.3 (109)
1.1 (1)
27.0 (24)
71.9 (64)
3.8 (7)
26.6 (49)
69.6 (128)
11.8 (17)
44.4 (64)
43.8 (63)
29.7 (35)
55.0 (65)
15.3 (18)
6.6 (12)
43.7 (79)
49.7 (90)
SLC16A9 (rs2242206 G > T) GG
CT
TT
54.9 (276)
37.0 (186)
8.1 (41)
32.9 (59)
44.1 (79)
23.0 (41)
15.2 (14)
51.1 (47)
33.7 (31)
16.9 (31)
55.2 (101)
27.9 (51)
34.7 (50)
40.3 (58)
25.0 (36)
31.9 (38)
47.1 (56)
21.0 (25)
33.0 (60)
55.5 (101)
11.5 (21)
GCKR
(rs780094 C > T)
CC
CT
TT
33.6 (169)
50.7 (255)
15.7 (79)
31.8 (57)
46.4 (83)
21.8 (39)
35.9 (33)
44.6 (41)
19.5 (18)
18.8 (35)
46.3 (86)
34.9 (65)
41.7 (60)
48.6 (70)
9.7 (14)
41.3 (50)
46.3 (56)
12.4 (15)
48.1 (88)
42.6 (78)
9.3 (17)
SLC22A11
(rs17300741G > A)
AA
AG
GG
23.5 (118)
45.5 (229)
31.0 (156)
73.6 (128)
23.5 (41)
2.9 (5)
80.2 (73)
18.7 (17)
1.1 (1)
71.7 (129)
26.1 (47)
2.2 (4)
54.0 (75)
36.7 (51)
9.3 (13)
53.3 (64)
32.5 (39)
14.2 (17)
62.6 (112)
31.8 (57)
5.6 (10)
SLC22A12
(rs505802 C > T)
CC
CT
TT
9.9 (50)
38.8 (195)
51.3 (258)
61.2 (112)
34.4 (63)
4.4 (8)
63.4 (59)
32.3 (30)
4.3 (4)
67.7 (126)
28.0 (52)
4.3 (8)
35.8 (52)
53.1 (77)
11.1 (16)
90.9 (110)
8.3 (10)
0.8 (1)
48.9 (90)
39.1 (72)
12.0 (22)
LRRC16A (rs742132 G > A) AA
AG
GG
48.3 (243)
41.4 (208)
10.3 (52)
48.9 (88)
41.7 (75)
9.4 (17)
60.4 (55)
35.2 (32)
4.4 (4)
62.4 (116)
31.7 (59)
5.9 (11)
30.2 (44)
56.8 (83)
13.0 (19)
51.7 (62)
36.7 (44)
11.6 (14)
25.2 (46)
52.8 (96)
22.0 (40)
PDZK1**
(rs12129861 C > T)
CC
CT
TT
30.4 (153)
47.3 (238)
22.3 (112)
42 (71)
5.4 (9)
52.6 (89)
54.3 (44)
4.9 (4)
40.8 (33)
47.8 (87)
2.2 (4)
50.0 (91)
36.3 (49)
5.9 (8)
57.8 (78)
37.7 (43)
3.5 (4)
58.8 (67)
42.2 (72)
8.7 (15)
49.1 (84)
  1. The bolded letter refers to the risk allele linked to hyperuricemia or gout
  2. Data from the 1000 Genomes Project Phase III
  3. **Allele deviated from HWE in all study subgroups