Predictive value of erythrocyte sedimentation rate and C-reactive protein in Behcet's disease activity and manifestations: a cross-sectional study

Table 1 Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values based on active manifestations of Behçet’s disease

BD active manifestations	Count (%)	ESR (mean ± SD) mm/hr	p-value	CRP (mean ± SD) mg/L	p-value
Active BD
Yes	450 (87.5%)	28.9 ± 23.8	< 0.001*	0	< 0.001*
No	64 (12.5%)	7.8 ± 4.5		0.9 ± 1.2
Active ocular signs
Yes	234 (45.5%)	20.7 ± 18.4	< 0.001*	0.6 ± 1	< 0.001*
No	280 (54.5)	30.9 ± 26		1 ± 1.3
Active oral signs
Yes	254 (49.4%)	35.2 ± 23.9	< 0.001*	1.2 ± 1.3	< 0.001*
No	260 (50.6%)	17.2 ± 19		0.4 ± 0.9
Active genital signs
Yes	99 (19.3%)	43 ± 21.7	< 0.001*	1.8 ± 1.2	< 0.001*
No	415 (80.7%)	22.3 ± 22		0.6 ± 1.1
Active vascular signs
Yes	36 (7%)	60.4 ± 20.2	< 0.001*	2.6 ± 1.1	< 0.001*
No	478 (93%)	23.7 ± 21.1		0.7 ± 1.1
Active joint signs
Yes	68 (13.2%)	50.2 ± 20.2	< 0.001*	1.8 ± 1.2	< 0.001*
No	446 (86.8%)	22.6 ± 21.6		0.6 ± 1.1
Active dermal signs
Yes	180 (35%)	36.7 ± 20.2	< 0.001*	1.4 ± 1.3	< 0.001*
No	336 (65%)	20.7 ± 23		0.5 ± 1
Positive pathergy test
Yes	106 (20.6%)	23.3 ± 25.5	0.017*	0.6 ± 1.2	0.011*
No	408 (79.4)	27 ± 22.8		0.8 ± 1.2
Epididymitis**
Yes	6 (1.2%)	50.1 ± 16.9	–	2.3 ± 1	–
No	508 (98.8%)	26 ± 23.3		0.8 ± 1.2
Active CNS signs**
Yes	7 (1.4%)	58.7 ± 38.5	–	1.8 ± 1.8	–
No	507 (98.6%)	25.8 ± 22.9		0.8 ± 1.2
Active GI signs**
Yes	2 (0.4%)	99 ± 33.9	–	3.5 ± 0.7	–
No	512 (99.6%)	26 ± 22.9		0.8 ± 1.2
Total	514	26.3 ± 23.4		0.8 ± 1.2

BD, Behçet’s disease; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; SD, standard deviation
*Statistically significant (Man-Whitney U test, p-value < 0.05)
**Insufficient number to fulfill the Mann–Whitney U test’s assumption of equal distribution

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