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Table 2 Summary of binary logistic regression models for predicting BD manifestations based on ESR and CRP

From: Predictive value of erythrocyte sedimentation rate and C-reactive protein in Behcet's disease activity and manifestations: a cross-sectional study

Condition

Variable

Wald

OR

95% CI

p-value

HS value

R square

AUC

95% CI

Active BD

ESR*

17.7

1.09

1.04–1.13

 < 0.001

0.58

0.32

0.79

0.74–0.83

 

CRP

0

–

–

0.99

  

0.71

0.66–0.76

Active vascular signs

ESR*

18.2

1.03

1.01–1.05

 < 0.001

0.78

0.37

0.85

0.79–0.92

 

CRP*

18.4

1.98

1.45–2.72

 < 0.001

  

0.86

0.8–0.91

Active ocular signs

ESR

12.2

0.98

0.97–0.99

 < 0.001

0.22

0.06

0.39

0.34–0.44

 

CRP

0.8

0.91

0.76–1.1

0.35

  

0.41

0.36–0.46

Active oral signs

ESR

30.5

1.03

1.02–1.04

 < 0.001

 < 0.001

0.23

0.74

0.7–0.79

 

CRP

11.7

1.41

1.15–1.71

0.001

  

0.69

0.64–0.73

Active genital signs

ESR

11.8

1.02

1.00–1.03

0.001

 < 0.001

0.23

0.78

0.73–0.82

 

CRP

25.0

1.67

1.36–2.04

 < 0.001

  

0.78

0.73–0.83

Active joint signs

ESR

30.5

1.03

1.02–1.05

 < 0.001

0.001

0.25

0.84

0.8–0.87

 

CRP

4.9

1.29

1.03–1.63

0.02

  

0.74

0.67–0.8

Active dermal signs

ESR

14.3

1.02

1.00–1.03

 < 0.001

 < 0.001

0.17

0.74

0.7–0.78

 

CRP

15.8

1.44

1.20–1.73

 < 0.001

  

0.70

0.65–0.75

Positive pathergy test

ESR

0.2

0.99

0.98–1.00

0.61

0.04

0.01

0.42

0.36–0.48

 

CRP

1.4

0.86

0.69–1.09

0.22

  

0.43

0.37–0.49

Epididymitis**

ESR

0.7

1.01

0.98–1.04

0.39

0.14

0.12

0.81

0.72–0.9

 

CRP

2.8

1.77

0.91–3.42

0.08

  

0.83

0.74–0.91

Active GI signs**

ESR*

3.9

1.07

1–1.15

0.04

1

0.5

0.97

0.94–1

 

CRP

0.8

2.41

0.36–16.04

0.36

  

0.94

0.88–0.99

Active CNS signs**

ESR*

6.0

1.03

1.00–1.06

0.01

0.77

0.14

0.77

0.59–0.95

 

CRP

0.05

1.07

0.56–2.00

0.82

  

0.65

0.41–0.9

  1. OR, odds ratio; CI, confidence interval; HS, Hosmer–lemeshow test; R square, Nagelkerke R square; AUC, area under the curve
  2. *Statistically significant p-value with statistically non-significant Hosmer–Lemeshow test (model fitness) and area under the curve > 0.7
  3. **Low number of patients with GI and CNS manifestations and epididymitis (0.4%, 1.4% and 1.2%, respectively) decreases the prediction model’s validity