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Table 1 Prevalence of cutaneous manifestations in POEMS syndrome [4]

From: Raynaud’s phenomenon and positive antinuclear antibodies as first manifestation of POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes): a case report

Feature

Patient (%)

Hyperpigmentation

50 (47)

Hemangioma

50 (47)

Hypertrichosis

41 (38)

Acrocyanosis

36 (34)

White nails

32 (30)

Sclerodermoid changes

28 (26)

Raynaud’s Phenomenon

21 (20)

Hyperemia/erythema

21 (20)

Flushing

17 (16)

Rubor

12 (11)

Clubbing

6 (6)