From: Pharmacist knowledge of gout management: impact of an educational intervention
Intervention assessment survey | Control n (%) | Intervention n (%) | p-value | ||
---|---|---|---|---|---|
Where is your primary area of practice? | Community | 25 (89%) | 23 (92%) | 0.74* | |
Hospital | 3 (11%) | 2 (8%) | |||
Urate-lowering therapy (ULT) is targeted to serum urate level | True | 19 (68%) | 24 (96%) | 0.006 | |
False | 5 (18%) | 1 (4%) | |||
Don’t Know | 4 (14%) | 0 (0%) | |||
First-line therapy for gout involves a combination of a xanthine oxidase inhibitor (e.g., allopurinol) combined with a prophylactic agent (e.g., colchicine) | True | 9 (32%) | 16 (64%) | 0.011 | |
False | 17 (61%) | 9 (36%) | |||
Don’t Know | 2 (7%) | 0 (0%) | |||
Colchicine at a dose of 0.5 mg twice daily should be given in combination with urate lowering therapy (ULT) for at least 6 months after initiation of ULT, as a prophylaxis for gout flares | True | 9 (32%) | 21 (84%) | 0.001 | |
False | 17 (61%) | 3 (12%) | |||
Don’t Know | 2 (7%) | 1 (4%) | |||
It is common for gout to flare when.. | Starting ULT | 1 (4%) | 7 (28%) | 0.053 | |
Stopping ULT | 4 (14%) | 1(4%) | |||
Increasing ULT | 0 (0%) | 0 (0%) | |||
All of the Above | 12 (43%) | 17 (68%) | |||
None of the above | 1 (4%) | 0 (0%) | |||
Patients should stop ULT during a gout attack | True | 7 (25%) | 1 (4%) | 0.10 | |
False | 20 (71%) | 24 (96%) | |||
Don’t Know | 1 (4%) | 0 (0%) | |||
Patients are advised to take colchicine continuously for six months or longer after initiation of ULT | True | 10 (36%) | 21 (84%) | 0.001 | |
False | 17 (61%) | 4 (16%) | |||
Don’t Know | 1 (4%) | 0 (0%) | |||
Patients should dose-reduce rather than stop colchicine if they experience side-effects (e.g., diarrhoea) | True | 16 (57%) | 18 (72%) | 0.24 | |
False | 11 (39%) | 6 (24%) | |||
Don’t Know | 1 (4%) | 1 (4%) | |||
Cost of medication is a factor in patient non-adherence | Agree | 9 (32%) | 6 (24%) | 0.36 | |
Neutral | 6 (21%) | 6 (24%) | |||
Disagree | 13 (46%) | 13 (52%) | |||
Which information sources for colchicine do you find helpful? | BNF | Yes | 20 (71%) | 18 (72%) | 1.0* |
No | 8 (29%) | 7 (28%) | |||
SPC | Yes | 15 (54%) | 14 (56%) | 0.59* | |
No | 13 (46%) | 11 (44%) | |||
Guidelines such as EULAR or ACR | Yes | 5 (18%) | 12 (48%) | 0.037* | |
No | 23 (82%) | 13 (52%) |