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Table 1 Clinical and biological features of a juvenile idiopathic arthritis family

From: Whole exome sequencing in a juvenile idiopathic arthritis large family with SERPINA1 gene mutations

Patients

III: 4

IV: 4

IV: 5

IV: 6

IV: 7

Age

40

20

17

16

13

Age of onset

8

11

8

10

8

Cesarean

N

Y

Y

Y

Y

Birth weight

2800

2700

3320

3340

3370

Breastfeeding ≥ 6 months

N

N

N

N

N

Maternal smoking during pregnancy

N

N

N

N

N

Passive smoking

N

N

N

N

N

Living in a rural area

Y

Y

Y

Y

Y

Living on a farm during first year of life

N

N

N

N

N

Household pets

Y

Y

Y

Y

Y

Periodontitis/rhinitis

N

N

N

N

N

Antibiotics exposure

N

N

N

N

N

Psoriasis

Y

N

N

Y

N

Asthma

Y

Y

N

N

Y

Serum alpha-1 antitrypsin

0.59 g per liter

0.99 g per liter

0.78 g per liter

0.68 g per liter

0.97 g per liter

  1. Y Yes, N No