From: Whole exome sequencing in a juvenile idiopathic arthritis large family with SERPINA1 gene mutations
Patients | III: 4 | IV: 4 | IV: 5 | IV: 6 | IV: 7 |
---|---|---|---|---|---|
Age | 40 | 20 | 17 | 16 | 13 |
Age of onset | 8 | 11 | 8 | 10 | 8 |
Cesarean | N | Y | Y | Y | Y |
Birth weight | 2800 | 2700 | 3320 | 3340 | 3370 |
Breastfeeding ≥ 6 months | N | N | N | N | N |
Maternal smoking during pregnancy | N | N | N | N | N |
Passive smoking | N | N | N | N | N |
Living in a rural area | Y | Y | Y | Y | Y |
Living on a farm during first year of life | N | N | N | N | N |
Household pets | Y | Y | Y | Y | Y |
Periodontitis/rhinitis | N | N | N | N | N |
Antibiotics exposure | N | N | N | N | N |
Psoriasis | Y | N | N | Y | N |
Asthma | Y | Y | N | N | Y |
Serum alpha-1 antitrypsin | 0.59Â g per liter | 0.99Â g per liter | 0.78Â g per liter | 0.68Â g per liter | 0.97Â g per liter |