Skip to main content

Table 2 Univariable associations between predictors and different outcomes of relapse

From: (Dis)agreement of polymyalgia rheumatica relapse criteria, and prediction of relapse in a retrospective cohort

Predictors Relapse within year 0–1 Relapse within year 0–2 Relapses per patient per year
OR 95% CI p OR 95% CI p IRR 95% CI p
Age (years) 1.00 0.98 0.92 0.92 1.00 0.76 1.02 0.76 1.00 0.99 1.01 0.87
Sex (reference category: male) 1.42 0.930 0.11 0.11 1.36 0.12 2.01 0.12 1.00 0.78 1.26 0.96
Positive medical history (reference category: no)             
Inflammatory disease 1.20 0.76 0.43 0.43 1.01 0.96 1.55 0.96 1.21 0.94 1.58 0.14
Malignancy 0.62 0.32 0.17 0.17 0.96 0.68 1.60 0.68 0.91 0.62 1.34 0.63
Cardiovascular disease 1.70 0.97 0.06 0.06 1.76 0.05 3.07 0.05 1.20 0.89 1.64 0.24
Smoking (reference category: no)1             
Stopped 0.87 0.50 0.61 0.61 1.18 0.52 1.96 0.52 1.29 0.96 1.74 0.09
Yes 0.82 0.42 0.57 0.57 1.00 0.99 1.86 0.99 0.97 0.67 1.40 0.86
Symptom duration before baseline
in months1
0.92 0.85 0.03 0.03 0.92 0.02 0.99 0.02 0.96 0.92 1.00 0.09
Clinical disease severity (score 0–8) 0.93 0.81 0.29 0.29 0.92 0.20 1.05 0.20 0.94 0.86 1.01 0.10
(Suspected) presence of peripheral arthritis
(reference category: no)
0.74 0.41 0.32 0.32 0.68 0.17 1.18 0.17 0.79 0.54 1.15 0.22
Presence of systemic symptoms
(reference category: no)
0.80 0.52 0.29 0.29 0.86 0.44 1.27 0.44 1.00 0.79 1.27 0.98
CRP per 10 mg/L2 1.08 1.01 0.02 0.02 1.09 0.01 1.16 0.01 1.04 1.01 1.08 0.03
ESR per 10 mm/h3 1.20 1.08 0.00 0.00 1.22 0.00 1.35 0.00 1.09 1.03 1.15 0.00
Hb per mmol/L4 1.03 0.75 0.88 0.88 0.99 0.94 1.32 0.94 1.03 0.86 1.25 0.73
  1. n, number; CRP, C-Reactive Protein; ESR, erythrocyte sedimentation rate; Hb, hemoglobin; APR, acute phase reactants; OR, odds ratio; CI, confidence interval; IRR, incidence rate ratio
  2. Bold, italic results show significance at a p value < 0.05. 1n = 411, 2n = 364, 3n = 396, 4n = 317