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Table 1 Baseline characteristics of AS patients and controls (combined group 40–89 years)

From: Malignancy in ankylosing spondylitis: a cross-sectional analysis of a large population database

Study group

Total AS

N = 

Missing

N (%)

AS patients w/cancer

N (%)

AS patients w/o cancer

N (%)

Total control

N = 

Missing

N (%)

Control w/cancer

N (%)

Control w/o cancer

N (%)

# of patients

10,940

 

1410 (12.9)

9530 (87.1)

13,344,160

 

2,055,530 (15.4)

11,288,630 (84.6)

Male

5180

 

760 (53.9)

4420 (46.4)

6,140,340

 

1,012,290 (49.2)

5,128,050 (45.4)

Female

5760

 

650 (46.1)

5110 (53.6)

7,214,190

 

1,044,170 (50.8)

6,170,020 (54.6)

White

8900

 

1210 (85.8)

7690 (80.7)

9,617,790

 

1,678,310 (81.7)

7,939,480 (70.3)

Black

940

 

90 (6.4)

850 (8.9)

1,321,400

 

169,780 (8.3)

1,151,620 (10.2)

Other races

 

1100 [10]

   

2,404,970 (18)

  

Active Smoker

2790

3280 (29.9)

430 (30.5)

2360 (24.8)

2,358,780

7,255,250 (54.4)

436,780 (21.3)

1,922,000 (17.0)

Ex smoker

3630

 

650 (46.1)

2980 (31.3)

2,855,190

 

703,690 (34.2)

2,151,500 (19.1)

Never smoker

1240

 

250 (17.7)

990 (10.4)

874,940

 

209,000 (10.2)

665,940 (5.9)

TNFi

4300

 

530 (37.6)

3770 (39.6)

39,100

 

6110 (0.3)

32,990 (0.3)

IL-17i

490

 

60 (4.3)

430 (4.5)

2950

 

440 (0.02)

2510 (0.02)

IBD

560

 

120 (8.5)

440 (4.6)

115,990

 

27,990 (1.4)

88,000 (0.8)

Uveitis

1390

 

210 (14.9)

1180 (12.4)

45,270

 

9970 (0.5)

3530 (0.03)

Psoriasis

1780

 

200 (14.2)

1580 (16.6)

185,260

 

40,110 (1.95)

145,150 (1.3)

  1. IBD: Inflammatory Bowel disease
  2. TNFIs: Infliximab, Etanercept, Adalimumab, Golimumab, Certolizumab
  3. IL-17i: Secukinumab, Ixekizumab