From: Malignancy in ankylosing spondylitis: a cross-sectional analysis of a large population database
Primary cancer | Group (40–89) | ||||
---|---|---|---|---|---|
AS with cancer N = (%) | Control with cancer N = (%) | Odds ratio | 95% CI | P value | |
Colon | 40 (2.8) | 135,450 (6.6) | 0.41 | [0.30, 0.57] | < 0.0001 |
Rectum and anus | 20 (1.4) | 61,920 (3.0) | 0.46 | [0.30, 0.72] | 0.0005 |
Head and neck | 60 (4.3) | 52,190 (2.5) | 1.71 | [1.32, 2.21] | < 0.0001 |
Thyroid | 30 (2.1) | 44,860 (2.2) | 0.97 | [0.68, 1.40] | 0.888 |
Lung | 60 (4.3) | 127,710 (6.2) | 0.67 | [0.52, 0.87] | 0.002 |
Breast | 100 (7.1) | 273,640 (13.3) | 0.50 | [0.41, 0.61] | < 0.0001 |
Malignant Melanoma | 100 (7.1) | 94,040 (4.6) | 1.59 | [1.30, 1.95] | < 0.0001 |
SCC | 130 (9.2) | 131,820 (6.4) | 1.48 | [1.24, 1.78] | < 0.0001 |
BCC | 230 (16.3) | 258,640 (12.6) | 1.35 | [1.18, 1.56] | < 0.0001 |
Bladder | 30 (2.1) | 59,590 (2.9) | 0.73 | [0.51, 1.05] | 0.084 |
Leukemia | 30 (2.1) | 58,400 (2.8) | 0.74 | [0.52, 1.07] | 0.107 |
Lymphoma | 70 (5.0) | 112,030 (5.5) | 0.91 | [0.71, 1.15] | 0.422 |
Non-Hodgkins | 60 (4.3) | 90,810 (4.4) | 0.96 | [0.74, 1.25] | 0.767 |