Predictors of severe lupus flare: a prospective follow-up study

BMC Rheumatology

Table 2 Continuous variables in lupus patients according to having severe lupus flare-up vs. no severe flare

Continuous characteristics of patients	Severe Lupus Flare-up				p
	No, N = 73		Yes, N = 47
	Mean	SD	Mean	SD
Age, years	38.30	8.24	31.70	7.89	0.001
Disease duration, years	11.23	7.46	9.04	7.15	0.10
Duration of follow-up, months	20.97	2.94	19.57	3.85	0.03
24-urine protein at the first visit, mg/dl	260.83	491.86	763.80	1011.56	0.0001
Creatinine at the first visit	0.90	0.27	0.93	0.20	0.6
BUN at the first visit	14.10	7.56	15.07	9.51	0.6
GFR at the first visit	88.97	22.06	92.50	23.40	0.4
ESR at the first visit	19.52	17.34	19.31	13.26	0.90
WBC at the first visit	5665	2248	6242	2382	0.2
Platelets at the first visit	221,411	73,905	239,893	75,201	0.2
Hemoglobin at the first visit	12.29	1.55	12.68	2.16	0.25
PGA at the first visit	0.29	0.68	1.12	1.29	0.0001
SLEDAI at the first visit	2.75	2.87	6.53	4.92	0.0001
Prednisolone dose at the first visit, mg/d	5.17	6.50	6.27	7.87	0.40
Cumulative dose of prednisolone, mg	2201	2332	4816	2870	0.0001

BUN, blood urea nitrogen; GFR, glomerular filtration rate; ESR, erythrocyte sedimentation rate; PGA, physician global assessment; SLEDAI, systemic lupus erythematosus activity index

ISSN: 2520-1026