Physical function and severe side effects matter most to patients with RA (< 5 years): a discrete choice experiment assessing preferences for personalized RA treatment

Table 3 Random parameter logit model

Attribute levels	Estimate (SE)	P value	CI	SD	P value (SD)	SE (SD)	CI (SD)	RI
Increase in physical functional capacity								1
25% improvement (ref^a)
50% improvement	2.32 (0.43)	< 0.01	1.47 – 3.16	0.19	N/A^b	0.33	-0.45 – 0.84
75% improvement	3.49 (0.45)	< 0.01	2.60 – 4.36	0.16	N/A	0.28	-0.38 – 0.70
100% full functional capacity	4.59 (0.53)	< 0.01	3.55 – 5.62	0.97	< 0.01	0.27	0.44 – 1.48
Increase in psychosocial functional capacity
25% improvement (ref)								0.35
50% improvement	0.83 (0.25)	< 0.01	0.34 – 1.32	0.02	N/A	0.34	-0.65 – 0.68
75% improvement	1.05 (0.26)	< 0.01	0.53 – 1.57	0.31	N/A	0.22	-0.12 – 0.73
100% full functional capacity	1.62 (0.29)	< 0.01	1.055 – 2.18	0.65	< 0.01	0.21	0.22 – 1.06
Frequency of mild side effects								0.33
Low (ref)
Medium	-0.41 (0.15)	< 0.01	-0.71 – (-0.11)	0.62	< 0.01	0.21	0.20 – 1.00
High	-1.52 (0.21)	< 0.01	-1.92 – (-1.11)	1.30	< 0.01	0.17	0.96–1.63
Likelihood of severe side effects								0.78
Rare: 1 in 1,000 (ref)
Common: 1 in 100	-0.94 (0.22)	< 0.01	-1.37 – (-0.49)	0.52	< 0.05	0.22	0.09 – 0.94
Very common: 1 in 10	-3.58 (0.39)	< 0.01	-4.35 – (-2.80)	2.64	< 0.01	0.31	2.04 – 3.22

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