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Table 2 Clinical difference between the patients with poor sleep quality and normal sleep quality

From: Sleep quality and clinical association with sleep disturbance in systemic sclerosis

Variable

Normal sleep quality

n = 40

Poor sleep quality

n = 48

OR (95%CI)

P-value

Female (%)

23 (57.5)

34 (70.8)

1.79 (0.68–4.78)

0.19

Age (years); median (IQR)

60.9 (57.5–64.4)

60.7 (57.5–63.9)

-

0.89

Age at onset (years); median (IQR)

53.6 (49.9–57.3)

50.8 (46.9–54.7)

-

0.30

BMI (kg/m2); mean ± SD

20.9 ± 4.1

21.2 ± 4.1

-

0.78

SSc subsets

 lcSSc (%)

16 (40.0)

16 (33.3)

1

NA

 dcSSc (%)

24 (60.0)

32 (66.7)

1.33 (0.50–3.48)

NA

mRSS (points); median (IQR)

2(0–6)

2(0–10)

-

0.53

Vasculopathy

 Active Raynaud’s phenomenon (%)

8 (20.0)

17 (35.4)

2.19 (0.75–6.72)

0.11

 Active Digital ulcer (s) (%)

1 (2.5)

7 (14.58)

6.66 (0.78–307.58)

0.045a

 Digital gangrene (%)

1 (2.5)

0 (0.0)

NA

NA

 Telangiectasia (%)

16 (40)

20 (41.7)

1.07 (0.42–2.75)

0.87

Musculoskeletal symptoms

 Tendon rub (%)

1 (2.5)

3 (6.3)

2.6 (0.19–139.91)

0.4

 Hand deformity (%)

13 (32.5)

21 (43.8)

1.65 (0.62–4.26)

0.28

 Synovitis (%)

4 (10.0)

5 (10.42)

1.05 (0.21–5.68)

0.95

Cardiopulmonary symptoms

 Cough (%)

9 (22.5)

13 (27.1)

1.23 (0.42–3.77)

0.67

 Chest pain (%)

0 (0.0)

1 (2.1)

NA

NA

Gastrointestinal symptoms

 Esophageal involvement (%)

21 (52.5)

18 (37.5)

0.54 (0.21–1.38)

0.15

 Heartburn (%)

15 (37.5)

13 (27.1)

0.62 (0.23–1.68)

0.30

 Stomach involvementb (%)

3 (7.5)

13 (27.1)

4.58 (1.10–26.74)

0.02a

 Intestinal involvement (%)

5 (12.5)

10 (20.8)

1.84 (0.51–7.52)

0.30

ILD (%)

26 (65)

26 (54.2)

0.63 (0.24–1.63)

0.30

Renal crisis (%)

1 (2.5)

0 (0.0)

NA

NA

Pulmonary hypertension (%)

7 (17.5)

4 (8.3)

0.43 (0.09–1.87)

0.19

Pain

 Joint pain (%)

12 (30.0)

13 (27.08)

0.84 (0.29–2.36)

0.70

 Muscle pain (%)

7 (17.5)

9 (18.8)

1.08 (0.32–3.84)

0.89

 Generalize pain (%)

1 (2.5)

3 (6.25)

2.59 (0.19–139.51)

0.40

 Low back pain (%)

4 (10.0)

13 (27.1)

3.34 (0.90–15.25)

0.04a

 Tooth pain (%)

2 (5.0)

3 (6.3)

1.26 (0.14–15.81)

0.80

 Headache (%)

1 (2.5)

6 (12.5)

5.56 (0.62–262.35)

0.09

Depressive disorder (%)

1 (2.5)

10 (20.8)

10.26 (1.32–456.49)

0.01a

Neck circumference (cm); mean ± SD

33.0 ± 2.6

32.6 ± 2.7

-

0.56

Mallampati classification

 I (%)

7 (17.5)

12 (25.0)

1

 

 II (%)

6 (15.0)

5 (10.4)

0.49 (0.11–2.20)

0.35

 III (%)

10 (25.0)

15 (31.3)

0.88 (0.26–2.99)

0.83

 IV (%)

17 (42.5)

16 (33.3)

0.55 (0.17–1.74)

0.31

  1. IQR interquartile range, OR odds ratio, 95%CI 95% confidence interval, lcSSc limited cutaneous systemic sclerosis, dcSSc diffuse cutaneous systemic sclerosis, ILD Interstitial lung disease, mRSS modified Rodnan skin score
  2. astatistically significant, NA not available due to statistical limitation (zero number of cases in one cell)
  3. ball dyspepsia