Table 1 Baseline Data For The Three Responder Groups

Sex, n (%)

Male

28 (17%)

10 (25%)

12 (16%)

6 (13%)

NS

Female

135 (83%)

30 (75%)

64 (84%)

41 (87%)

Ethnicity, n (%)

White

151 (93%)

38 (95%)

71 (93%)

42 (89%)

NS

Black

6 (4%)

0 (0%)

3 (4%)

3 (6%)

Asian

3 (2%)

1 (3%)

2 (3%)

0 (0%)

Mixed

1 (1%)

1 (3%)

0 (0%)

0 (0%)

Other ethnic group

2 (1%)

0 (0%)

0 (0%)

2 (4%)

Smoking, n (%)

Never smoked

56 (34%)

17 (43%)

24 (32%)

15 (32%)

NS

Ever smoked

104 (64%)

22 (55%)

51 (67%)

31 (66%)

Missing

3 (2%)

1 (3%)

1 (1%)

1 (2%)

Age (Years) Mean (SD)

56.2 (12.1)

55.3 (13.3)

57.3 (12.1)

55.3 (11.2)

NS

Disease Duration (Years) Mean (SD)

6.6 (6.8)

6.1 (5.6)

6.5 (6.1)

7.2 (8.6)

NS

BMI Mean (SD)

28.8 (8.6)

25.1 (4.7)

28.7 (6.2)

32.1 (12.5)

< 0.001

DAS28-ESR Mean (SD)

4.4 (0.5)

4.2 (0.6)

4.3 (0.5)

4.7 (0.4)

< 0.001

Tender Joint counts (28 joints) Mean (SD)

7.3 (4.0)

7.1 (3.9)

7.0 (4.4)

7.8 (3.5)

NS

Swollen joint counts (28 joints) Mean (SD)

4.2 (3.0)

4.6 (3.8)

4.1 (2.8)

4.1 (2.6)

NS

Erythrocyte Sedimentation Rate (mm/hr) Mean (SD)

17.9 (13.9)

12.4 (9.9)

18.4 (15.4)

21.6 (13.2)

0.008

C-Reactive Protein (mg/L) Mean (SD)

8.4 (10.6)

5.9 (6.8)

9.9 (13.2)

8.2 (8.0)

NS

Assessor Global Rating (mm) Mean (SD)

39 (18)

40 (22)

37 (18)

42 (15)

NS

Patient Global Assessment (mm) Mean (SD)

43.1 (19.1)

44.8 (22.6)

41.8 (18.9)

43.6 (16.3)

NS

HAQ Mean (SD)

1.2 (0.7)

0.9 (0.6)

1.3 (0.7)

1.5 (0.6)

< 0.001

Pain (mm) Mean (SD)

40 (23)

37 (26)

40 (23)

44 (19)

NS

Fatigue (mm) Mean (SD)

59 (25)

48 (30)

61 (23)

64 (21)

0.006

Patient Health Questionnaire-9 Mean (SD)

8.5 (6.1)

6.4 (4.9)

8.2 (5.9)

10.7 (7.0)

0.004