Fig. 4
A Transverse section of pulmonary vessel with near complete occlusion of lumen (black arrow) by tumour. The tumour is confined within the tunica media (white arrow) with no invasion through the vessel wall. Haematoxylin and eosin stain, x1 magnification. B Sheets of pleomorphic tumour cells with admixed spindled cells (straight white arrow) and large multinucleate cells (bent white arrow). Haematoxylin and eosin stain, x10 magnification. C Tumour within pulmonary vessel (black arrow) with surrounding tunica media (white arrow). Haematoxylin and eosin stain, x10 magnification. D Tumour cells with positive staining for Murine Double Minute Clone 2, ranging from a weak blush to focally strong nuclear staining (white arrow). Haemotoxylin stain with bluing reagent, x20 magnification