Fig. 2

Differences in the expression of inflammasomes in different groups. (A) NLRP1 mRNA levels in the DAS28-CRP > 5.1 (high activity group), 3.2 < DAS28-CRP < 5.1 (moderate activity group), and 2.6 < DAS28-CRP < 3.2 (low activity group) groups were noticeably lower than those in the HC group, but there were no significant differences between the DAS28-CRP < 2.6 (remission group) and HC groups. (B) NLRP3 mRNA levels in the inactive and active groups were higher than those in the HC group. (C) Caspase-1 mRNA levels in the inactive and active groups were higher than those in the HC group. (D) AIM2 mRNA levels in the inactive group were higher than those in the HC group and the active group. IA, inactive group; A, active group