Table 1 Clinical details of the RA and HC groups

Demographics

 Sex, male/female

10/20

5/11

 Age (range)

55 (31–75)

57 (40–72)

 BMI (kg/m²)

22.4 ± 4.1

 Smoking (Yes/No)

8/22

 Alcohol drinking (Yes/No)

10/20

Clinical characteristic

 Disease duration, years (range)

6.37(0.3–16)

 DAS28-CRP

3.66 ± 1.79

 RF, IU/ml

255.20 ± 237.70

 Anti-CCP, RU/ml

366.90 ± 476.27

 ESR, mm/h

36.60 ± 27.52

 CRP, mg/l

16.91 ± 22.07

 plasma IL-1beta, pg/ml

6.62 ± 1.65^***

4.93 ± 0.98

 plasma IL-18, pg/ml

759.79 ± 661.36^**

307.89 ± 230.42

 WBC, 10⁹/l

5.96 ± 1.87

5.38 ± 1.25

 N, 10⁹/l

3.87 ± 1.64

2.97 ± 1.01

 M, 10⁹/l

0.43 ± 0.17

0.39 ± 0.09

 L, 10⁹/l

1.78 ± 1.16^*

1.86 ± 0.37

Treatments

 Glucocorticoids, n (%)

12 (40%)

 Methotrexate, n (%)

18 (60%)

 Biologic agents, n (%)

8 (27%)

 JAK inhibitors, n (%)

5 (17%)